Protein Alignment AMPKalpha and chk1

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001342786.1
• Gene: chk1 / 2539087
• PomBaseID: SPCC1259.13
• Length: 496
• Species: Schizosaccharomyces pombe
• Alignment Length: 342
• Identity: 104/342 - (30%)
• Similarity: 168/342 - (49%)
• Gaps: 53/342 - (15%)

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVG----KIRREIQNLKLFR-HPH 87
            |.:|..:|||.|..|::......:: .|||.:|::...|....|    ::..|||..||.. |.:
pombe    10 YHIGREIGTGAFASVRLCYDDNAKI-YAVKFVNKKHATSCMNAGVWARRMASEIQLHKLCNGHKN 73

  Fly    88 IIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDL 152
            ||..|.....|...::::|:..||:|||.|.....:.|..|:.:|.|::.|:.:.|...:.||||
pombe    74 IIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHSKGVAHRDL 138

  Fly   153 KPENLLLDHNMHVKIADFGLSNMML---DGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGV 214
            ||||:|||:|.::||:|||.:::..   ....|.:..|||.|||||:.  :.|.|.:||:||||:
pombe   139 KPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEIT--QQYDGSKVDVWSCGI 201

  Fly   215 ILYALLCGTLPFDDEHVPT----LFRKIKSGIFPIPEY-----LNKQVVNLVCQMLQVDPLKRAN 270
            ||:|||.|..|:|:....|    |::|....    |.|     |:....:::..||:.||.||.:
pombe   202 ILFALLLGNTPWDEAISNTGDYLLYKKQCER----PSYHPWNLLSPGAYSIITGMLRSDPFKRYS 262

  Fly   271 IEEIKKHEWFQKDLPAYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335
            ::.:.:|.|.....|   |.:   ::.|..|..|:|                       .:|.:.
pombe   263 VKHVVQHPWLTSSTP---FRT---KNGNCADPVALA-----------------------SRLMLK 298

  Fly   336 YHLIIDNKRFADDAANQ 352
            ..:.:|..|.|...|:|
pombe   299 LRIDLDKPRLASSRASQ 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	91/268 (34%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	10/56 (18%)
		AMPKA_C	457..580	CDD:213378
chk1	NP_001342786.1	STKc_Chk1	8..272	CDD:270971	91/268 (34%)