DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AMPKalpha and Tssk2

DIOPT Version :10

Sequence 1:NP_477313.1 Gene:AMPKalpha / 43904 FlyBaseID:FBgn0023169 Length:582 Species:Drosophila melanogaster
Sequence 2:NP_033462.2 Gene:Tssk2 / 22115 MGIID:1347559 Length:358 Species:Mus musculus


Alignment Length:347 Identity:118/347 - (34%)
Similarity:188/347 - (54%) Gaps:17/347 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLY 92
            |::|..||.|::.|||....:..:..|||||::|:|..:..|...:.||:..|....|..|||.|
Mouse    12 YIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRSIIKTY 76

  Fly    93 QVISTPSD--IFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPE 155
            ::..| ||  |:::||....|:|.::|...|.|.|..||:.|:|:.|.|.|||...:||||||.|
Mouse    77 EIFET-SDGRIYIVMELGVQGDLLEFIKCRGALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCE 140

  Fly   156 NLLLDHNMHVKIADFGLSNMML-DGE----FLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVI 215
            |||||.:.::|::|||.|...| ||.    ..:|.|||..||||||:.|..|.....||||.|||
Mouse   141 NLLLDKDFNIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVI 205

  Fly   216 LYALLCGTLPFDDEHVPTLFR--KIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHE 278
            ||.::||::|:||..:..:.|  |.....||..:.|..:..:|:.::||.|..:|.:|:||..|.
Mouse   206 LYIMVCGSMPYDDSDIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHS 270

  Fly   279 WFQKDLPAYLFPSSIEQDSNVIDTY-AVAEVCTKFGVKETEVHNSLLSGDPHDQLAIAYHLIIDN 342
            |.|...|..:..:|.:::..  ..| |..::.|:.|.:.....:..|:..|..::.:.    .:|
Mouse   271 WLQPPKPKAMSSASFKREGE--GKYRADCKLDTRPGSRPEHRPDHKLATKPQQRMLVT----PEN 329

  Fly   343 KRFADDAANQINEINNFFVAGS 364
            :...:|...:.:...:..::|:
Mouse   330 EDRMEDRLAETSRAKDHHISGA 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AMPKalphaNP_477313.1 STKc_AMPK_alpha 25..280 CDD:270981 105/260 (40%)
UBA_AID_AMPKalpha 297..360 CDD:270521 8/63 (13%)
AMPKA_C 457..580 CDD:213378
Tssk2NP_033462.2 STKc_TSSK1_2-like 10..272 CDD:271067 105/260 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 296..358 7/60 (12%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.