Protein Alignment AMPKalpha and Tssk1

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_033461.2
• Gene: Tssk1 / 22114
• MGIID: 1347557
• Length: 365
• Species: Mus musculus
• Alignment Length: 264
• Identity: 108/264 - (40%)
• Similarity: 160/264 - (60%)
• Gaps: 12/264 - (4%)

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGK-IRREIQNLKLFRHPHIIKL 91
            |::|..||.|::.|||....:..:..|||||::|:|..| |.:.| :.|||:.|.:..|..|:|.
Mouse    12 YIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPS-DFLEKFLPREIEILAMLNHRSIVKT 75

  Fly    92 YQVISTPSD--IFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKP 154
            |::..| ||  ::::||....|:|.::|...|.|||..||:.|.|:.|.:.|||...:||||||.
Mouse    76 YEIFET-SDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLDVVHRDLKC 139

  Fly   155 ENLLLDHNMHVKIADFGLSNMML---DGEFL--RTSCGSPNYAAPEVISGKLYAGPEVDIWSCGV 214
            ||||||.:.::|::|||.|...|   .|..:  :|.|||..||||||:.|..|.....||||.||
Mouse   140 ENLLLDKDFNIKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGV 204

  Fly   215 ILYALLCGTLPFDDEHVPTLFR--KIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKH 277
            |||.::||::|:||.::..:.|  |.....||..::|..:..:|:.:|||.|..:|.:|:||..|
Mouse   205 ILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYRMLQPDVNRRLHIDEILNH 269

  Fly   278 EWFQ 281
            .|.|
Mouse   270 CWVQ 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	106/261 (41%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
Tssk1	NP_033461.2	STKc_TSSK1_2-like	10..271	CDD:271067	106/260 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..365