Protein Alignment AMPKalpha and Snrk

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_321330.6
• Gene: Snrk / 1281422
• VectorBaseID: AGAMI1_007528
• Length: 1220
• Species: Anopheles gambiae
• Alignment Length: 347
• Identity: 122/347 - (35%)
• Similarity: 194/347 - (55%)
• Gaps: 27/347 - (7%)

  Fly    11 AVAAGSANGQPLVKI-GHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGK-- 72
            |..||..:|    || |.|.|..|||:|.|..||:..|..|..|||||::.:.|   ||.:.:
Mosquito    11 ASRAGVYDG----KIAGLYDLEETLGSGHFAVVKLARHVFTGEKVAVKVIEKTK---LDEISRAH 68

  Fly    73 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGK-LQEHQARRFFQQII 136
            :.:|::.:||.:||::::||:||.|.:.:::|:|...||:|:|||::|.| |.|:.||.:|:||:
Mosquito    69 LFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILELGDGGDLYDYIMRHEKGLSENVAREYFRQIV 133

  Fly   137 SGVDYCHRHMIVHRDLKPENLLLDHNMH-VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGK 200
            ..:.|||:..:|||||||||::....:. ||:.|||.||....|:.|.|||||..|:|||::.|.
Mosquito   134 RAISYCHQLHVVHRDLKPENVVFFEKLGVVKLTDFGFSNKFCPGQKLETSCGSLAYSAPEILLGD 198

  Fly   201 LYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDP 265
            .|..|.||:||.||||:.|:||..||.:.:.......|....:.:|.:::....||:.:||..:|
Mosquito   199 SYDAPAVDVWSLGVILFMLVCGHPPFQEANDSETLTMIMDCKYTMPAHVSDGCRNLISKMLVREP 263

  Fly   266 LKRANIEEIKKHEWFQ--------KDLPAYLFPSSIEQDSN-VIDTYAVAEVCTKFGVKETEVHN 321
            .|||.:::|....|..        ::.|........|:|.. :|......::.||..:.|.
Mosquito   264 EKRATLQQIALDVWLMEGSCEETPENQPLVSREQVSEEDHTLIIQKMINGKIATKEEILEA---- 324

  Fly   322 SLLSGDPHDQLAIAYHLIIDNK 343
              |..:.::.:...|.|:.:.|
Mosquito   325 --LDRNEYNHITATYFLLAERK 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	105/259 (41%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	8/48 (17%)
		AMPKA_C	457..580	CDD:213378
Snrk	XP_321330.6	None