Protein Alignment AMPKalpha and grp

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_061516706.1
• Gene: grp / 1277834
• VectorBaseID: AGAMI1_013651
• Length: 518
• Species: Anopheles gambiae
• Alignment Length: 298
• Identity: 101/298 - (33%)
• Similarity: 161/298 - (54%)
• Gaps: 40/298 - (13%)

  Fly     8 AAEAVAAGSANGQPLVKIGHYL----LGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLD 68
            ||.....||.||.....:..::    |..|||.|.:|:||:..::.:...||:|:::.:  |..|
Mosquito     2 AASQTVVGSGNGGTQSGLREFVEGWTLAQTLGEGAYGEVKLLINRQSGEAVAMKMVDLK--KHPD 64

  Fly    69 VVGKIRREIQNLKLFRHPHIIKLYQVISTPSDI-FMIMEYVSGGELFDYIVKHGKLQEHQARRFF 132
            ....:::|:...|:.:|.:|:|.:.. .|..|| ::.:||.:||||||.|.....:...:|:|:|
Mosquito    65 AESSVKKEVCIQKILQHQNILKFFGK-RTQGDIEYIFLEYAAGGELFDRIEPDVGMPLPEAQRYF 128

  Fly   133 QQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMM-LDG--EFLRTSCGSPNYAAP 194
            .|:::||||.|...:.||||||||||||.:.:|||:|||::.|. :.|  ..|...||:..|.||
Mosquito   129 NQLLAGVDYLHTRGVAHRDLKPENLLLDEHDNVKISDFGMATMFRMKGRERLLDKKCGTLPYVAP 193

  Fly   195 EVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYL----NKQ--- 252
            ||:. |.|.....|:||||:||..:|.|.||:|..         .||   ..|||    ||.
Mosquito   194 EVLV-KPYRATPADLWSCGIILVTMLAGELPWDQP---------SSG---CAEYLCWKENKYTTS 245

  Fly   253 ---------VVNLVCQMLQVDPLKRANIEEIKKHEWFQ 281
                     .::|:.::|..:|.:|..:::::.|:|.|
Mosquito   246 TPWCKLDTLTLSLLRKILVANPAQRLTLDKLQDHKWCQ 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	93/278 (33%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
grp	XP_061516706.1	None