Protein Alignment AMPKalpha and LOC101887148

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_005162419.1
• Gene: LOC101887148 / 101887148
• -ID: -
• Length: 731
• Species: Danio rerio
• Alignment Length: 488
• Identity: 157/488 - (32%)
• Similarity: 246/488 - (50%)
• Gaps: 57/488 - (11%)

  Fly    24 KIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGK-IRREIQNLKLFRHPH 87
            ::|.||:|..:..|:|.||.:|.:..|..|||:|:::::|.:....|.| ::||.:..:|.|||:
Zfish    43 RVGSYLVGKMINKGSFAKVMLGMNISTGEKVAIKVIDKKKARQDSYVLKNMKREPRIHQLIRHPN 107

  Fly    88 IIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDL 152
            |:.|.:.:.|.:..:|.||...||:|.|.|.:..:|.|.:.|||.:||:|.|::.|||.||||||
Zfish   108 IVLLLETLETENCYYMAMELCGGGDLMDRICERKRLDEREVRRFTRQILSAVEHLHRHGIVHRDL 172

  Fly   153 KPENLLLDHNMHVKIADFGLSNMM----LDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCG 213
            |.||.|||.:.::||.||||||.:    |..:.|.|.||||.|||||:::.|.| ||:||:||.|
Zfish   173 KIENFLLDEHNNIKIVDFGLSNTLKGDSLSVDLLNTQCGSPAYAAPELLAHKKY-GPKVDVWSVG 236

  Fly   214 VILYALLCGTLPFDDE--HVPTLFRKIKSG-IFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIK 275
            |.::|:|.|||||..|  ::..|.:|:.:| |.|||..::|..|..|..:|:.:|.||..::...
Zfish   237 VSMFAMLTGTLPFTVEPFNIKQLHQKMVNGEISPIPSDISKAAVEFVLSLLEPEPAKRPTVKAAM 301

  Fly   276 KHEWF-----QKDLPAYLFPSSIE-QDSNVIDTYAVAEVCTK---FGVKETEVHNSLLSGDPHDQ 331
            :.:|.     ::.|...:..:.:. :|.|    .||....|:   ||:  ::|.::::|..|...
Zfish   302 EDKWLNEGYAKRPLHTVIHKNRMRPEDLN----SAVLNYMTESLGFGL--SDVIHTVISNKPSAI 360

  Fly   332 LAIAYHLIIDN-----------KRFADDAANQINE-----INNFFVAGSPPPPPPPPVPQSSMDH 380
            || .|||::..           ||..:...|.:|:     .:|.........|......:.| ..
Zfish   361 LA-CYHLLLKKLTRHQKVVRSMKREENSEWNLLNKGLSRGRSNASAKSQQQSPQSDSANERS-SR 423

  Fly   381 QAPLATVTVGGGTSASSGTATPVPPVAGGTPSSTIPIRPHPERIAPMRD--RQLAMSVQTSGG-- 441
            ||..:..:......|.||...|...   ..|..|..:.......:|.:|  .::.:.|:|..|
Zfish   424 QASKSQRSQSQDRDAQSGMKRPAET---SRPKQTSLVDRADSPASPPKDTANEITILVETHDGLN 485

  Fly   442 ---GAFPEKTARGGTPIKRAKWHLGIRSQSKPN 471
               .||.||......|.|     ...|..|.||
Zfish   486 PKVSAFVEKDLLHVCPPK-----CSCRDASDPN 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	110/262 (42%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	19/81 (23%)
		AMPKA_C	457..580	CDD:213378	4/15 (27%)
LOC101887148	XP_005162419.1	Protein Kinases, catalytic domain	44..306	CDD:473864	110/262 (42%)