Protein Alignment AMPKalpha and LOC100911229

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_038951080.1
• Gene: LOC100911229 / 100911229
• RGDID: 6494469
• Length: 654
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 163/594 - (27%)
• Similarity: 260/594 - (43%)
• Gaps: 121/594 - (20%)

  Fly    27 HYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKL 91
            ||.:.|:||.|.||:||:..|.:|:.|||:|:|.:.....|     ::.||:.:|...|||||||
  Rat    23 HYRILASLGQGGFGEVKLASHLLTQTKVAIKVLPKSNKNLL-----LKSEIEIMKSLDHPHIIKL 82

  Fly    92 YQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPEN 156
            ..:|.|..:||:::|:..||||...|...|.|.|.:..|.|:|::..:.|||:..|:|||:||||
  Rat    83 LHIIDTNENIFIVLEHAVGGELLTRIEDFGYLPEEECNRLFRQMVLALQYCHQRGIIHRDIKPEN 147

  Fly   157 LLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLC 221
            :||||..:||::|||||..::.|:.|.|.||:..|.|||:.:...|.|..:|:||.||:||.:..
  Rat   148 ILLDHKGNVKLSDFGLSTKIVMGQKLTTLCGTLPYCAPELFNLNGYDGQAIDVWSLGVVLYYMAT 212

  Fly   222 GTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPA 286
            |.|||.......:.:||.||.:.:...|:..:.:::.::|.|:|.:|..:.||.:..|.:.:  .
  Rat   213 GCLPFQGFTYQAIKQKILSGRYSVNFRLSPDLWDVIAKLLTVNPRERPRVHEILRFNWLKNE--N 275

  Fly   287 YLFPSSI--EQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIAYHLIIDNKRFADD- 348
            .:.|||:  ..||:...|..|  :....|.::.::..||.. ...||: :|.:|::..|..::|
  Rat   276 EVSPSSLGGNTDSHPDPTILV--MMGDMGYEQGQIRESLRE-RKFDQV-MATYLMLREKACSEDK 336

  Fly   349 ---------------AANQINEINNFFVAGSPPPP-----PPPPV------PQSSMDHQAPLATV 387
                           :.....|.......||..|.     .|..:      .:::|.|..|....
  Rat   337 SIKTPHPTQCAQTLKSTGSTTEKQTTLRRGSSLPTLTTFYLPSKLESLNKEKRTTMRHTMPPNLN 401

  Fly   388 TVGGGTSASSGTATPVPPVAGGT-----------------------PSSTIPIRPHPERIAPMRD 429
            ......|.:.|..|.|......|                       |..|.|:|    ||.|...
  Rat   402 CFNKSESLNKGRRTIVSHTISPTLNCFNKPESLNKGKRTIVRHTMPPKKTSPVR----RICPRLH 462

  Fly   430 RQLAMSVQTSGGGAFPEKTARGGTPIKRAKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIINPY 494
            :...|       |:..|.:::              |:.|.|:..:......|.|..|.    :.|
  Rat   463 KSFGM-------GSASEDSSK--------------RNSSDPSLTIFSSQSFMSAFKYG----STY 502

  Fly   495 HVRVRRQNVKTGKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDVIMES----LTPPPLSVSG 555
            ..|            |..||.        :|.:.:  :.|.:|....|:.|    .|.||   :.
  Rat   503 SKR------------KAFLQC--------ILHYHA--SQEEDQYKTTIIPSGKLNTTVPP---NS 542

  Fly   556 VMPLQPTGH 564
            :...|||||
  Rat   543 LQEDQPTGH 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	99/252 (39%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	13/78 (17%)
		AMPKA_C	457..580	CDD:213378	24/112 (21%)
LOC100911229	XP_038951080.1	STKc_AMPK-like	23..270	CDD:270905	99/251 (39%)
		UBA_MARK_Par1	290..329	CDD:270522	9/42 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010