Protein Alignment AMPKalpha and brsk2b

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_009301700.1
• Gene: brsk2b / 100149571
• ZFINID: ZDB-GENE-100422-3
• Length: 886
• Species: Danio rerio
• Alignment Length: 596
• Identity: 203/596 - (34%)
• Similarity: 304/596 - (51%)
• Gaps: 122/596 - (20%)

  Fly    25 IGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHII 89
            :|.|.|..|||.|..|.||:|.|.:|..|||:||:||:|: |..|:.|:.|||..|||..|||::
Zfish    17 VGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKL-SESVLMKVEREIAILKLIEHPHVL 80

  Fly    90 KLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKP 154
            ||:.|......:::::|:|||||||||:||.|:|...:||:||:||||.:|:||.|.|.||||||
Zfish    81 KLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKP 145

  Fly   155 ENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYAL 219
            ||||||...:::|||||::::.:....|.||||||:||.||||.|:.|.|.:.|:|||||||:||
Zfish   146 ENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFAL 210

  Fly   220 LCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWF---- 280
            |.|.|||||:::..|..|:|.|:|.:|.::.....||:..|::||..||..:|:|:||.|:
Zfish   211 LVGALPFDDDNLRNLLEKVKLGVFHMPHFIPPDCQNLLRGMIEVDATKRLTLEQIQKHTWYIGGK 275

  Fly   281 -----QKDLPAYL----FPSSIEQDSNVIDT-YAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335
                 ::.:|..:    .||:.:.|.:|::: :::.  |.:   .:.::...|||.|.:.:..|
Zfish   276 NEPEPEQPVPRKVAIRTLPSTEDIDPDVLESMHSLG--CFR---DKNKLMKDLLSDDDNQEKMI- 334

  Fly   336 YHLIIDNK-RFADDAANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLAT------------- 386
            |.|::|.| |:..      :|..|.      ||......|:..:|  :||.|
Zfish   335 YFLLLDRKERYPS------HEDQNL------PPRNEIDPPRKRVD--SPLLTRHNKRRPERKSME 385

  Fly   387 ---VTVGGGTSASSGTATPVP-----PVAGGTPSSTI-----------PIRPHPERIAPMRDRQL 432
               ||.||         :|||     .:|....|.::           ||....|      :|..
Zfish   386 VLSVTEGG---------SPVPVRRAIDMAQHGQSKSVFSKSLDISDANPILQSKE------ERSR 435

  Fly   433 AMSVQTSGGGAFPEKTARGGTPIKRAKWHLGIRSQS-----KPNDIMLEVYRAMKALSYEWKIIN 492
            ::|..:||....|..:.|   |::|    ..:..||     .||.                   :
Zfish   436 SISGASSGLSTSPLSSPR---PMRR----FAVPPQSSDLTYSPNH-------------------S 474

  Fly   493 PYHVRVRRQNVKTGKFS-KMSL---QLYQVDAKSYLLDFKSLTNDEVEQG--DDVIMESLTPPPL 551
            |.|..|.|.| .||..| |:.|   ...|::.|:..|..|....|:..|.  .:.:..|...||:
Zfish   475 PTHAPVARLN-GTGPHSPKIFLPKTAADQLNNKTQTLPAKPKVADKPLQATRSNPLPNSTPVPPV 538

  Fly   552 SVS-GVMPLQP 561
            :.| ...|.||
Zfish   539 AKSEPSTPCQP 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	130/254 (51%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	14/64 (22%)
		AMPKA_C	457..580	CDD:213378	28/117 (24%)
brsk2b	XP_009301700.1	STKc_BRSK1_2	18..271	CDD:270983	130/253 (51%)
		S_TKc	20..270	CDD:214567	129/250 (52%)
		UBA_BRSK	298..351	CDD:270525	14/64 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910