DRSC/TRiP Functional Genomics Resources

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Protein Alignment chb and Togaram2

DIOPT Version :9

Sequence 1:NP_524651.2 Gene:chb / 43901 FlyBaseID:FBgn0021760 Length:1491 Species:Drosophila melanogaster
Sequence 2:XP_017449897.2 Gene:Togaram2 / 313892 RGDID:1310677 Length:1184 Species:Rattus norvegicus


Alignment Length:552 Identity:113/552 - (20%)
Similarity:216/552 - (39%) Gaps:122/552 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 LTGSHFKIAQKSLEAFSELIKRLGSDFNAYTATVLPHVIDRLGDSRDTVREKAQLLLRDLMEHRV 122
            :|....|:::.::....:|.:.|....:.....::..::.::|::.:.::..|...|..::|: |
  Rat   697 VTNLRSKVSRLAISTLGDLFRALKKSMDQEAEEIVRCLLQKMGNTSEFIQRAANRALGAMVEN-V 760

  Fly   123 LPPQALIDKLATSCFKHKNAKVREEFLQTIVNALHEYGTQQLSVRVYIPPVCALLG--DPTVNVR 185
            .|.:||: .|.::...|:|..||:...:.:...|.:.|.::|           |.|  |.|    
  Rat   761 TPARALV-ALTSAGVYHRNPLVRKCTAKHLSAVLEQIGAEKL-----------LSGSRDNT---- 809

  Fly   186 EAAIQTLVEIYKHVGDRLRPDLRRMDDVPASKLAMLEQKFD-----------------QVKQEGL 233
            :..:..||.:.:......|...|:|.::     .|...|||                 .:||.|:
  Rat   810 DMLVHNLVRLAQDSNQDTRFYGRKMVNI-----LMANAKFDAFLKQSLPSHDLRKVMAAIKQRGI 869

  Fly   234 LLPSALKNTNGNGV--GLDEADNIGLRERPTRMIKRPLHSAVSSSLRPKPNVNDVTGDAGAVTME 296
            .....|.:..|..|  .|...:| ||   |::...:||       |.|:...|   |........
  Rat   870 QDNHELPSAKGRKVLKSLVVCEN-GL---PSQEGGQPL-------LPPRLGSN---GPRLVGLRS 920

  Fly   297 SFESSFEVVPQLNIFHAKDMDDIYKQVLVIISDKNADWEKRVDALKKIRALLILSY-HTQPQFVA 360
            |.....|:..||            :::..::..|  :::.|::.:.|     :|.| .|:|:.||
  Rat   921 SMRGGVEMAEQL------------RELTRLLEAK--EFQARMEGVGK-----LLEYCKTKPEHVA 966

  Fly   361 VQLKELSLSFVDILKEELRSQVIREACITIAYMSKTLRNKLDAFCWS-ILEHLINLIQNSAKVIA 424
            ..|.::..:|...|.:. ..:|.:.|..::|.|...||..:.....| |:....||...::.:..
  Rat   967 ANLVQVFDAFTPRLHDS-NKKVNQWALESLAQMLPILRESIHPMLLSLIIVAADNLNSKNSGIST 1030

  Fly   425 SASTI------ALKYI---------IKYTHAPKLLKIYTDTLNQSKSKDIRSTLCELMVLLFEEW 474
            :|||:      :|.::         :::...|.:|             |:...|..|:..::.. 
  Rat  1031 AASTVLDAMMDSLDHLCLLQAFAGRVRFLTGPAVL-------------DVTDRLSALVASVYPR- 1081

  Fly   475 QTKALERN-ATVLRDTLKKSIGDADCDAR-RHSRYAYWAFRRHFPELADQIYGTL-DIAA---QR 533
            :.:|:||: ..||...|.|..|:.....| .:.|.|.....|   .|.:|:...| |.||   |:
  Rat  1082 KPQAVERHILPVLWYFLNKMTGNGVLPGRGGNVRTAVCRLAR---SLQEQMGSRLQDFAANQPQQ 1143

  Fly   534 ALERER-----EGGGGGGTGTGTGTAPETRRT 560
            ||:..:     |..|.....|..|.||:.:.|
  Rat  1144 ALKTLQGLLVSESLGDNNKVTSGGMAPDIQMT 1175

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
chbNP_524651.2 HEAT repeat 50..78 CDD:293787 3/19 (16%)
CLASP_N <74..211 CDD:289144 26/138 (19%)
HEAT repeat 90..120 CDD:293787 3/29 (10%)
HEAT_2 129..>210 CDD:290374 16/82 (20%)
HEAT repeat 131..154 CDD:293787 5/22 (23%)
HEAT repeat 165..195 CDD:293787 6/31 (19%)
CLASP_N 316..536 CDD:289144 51/242 (21%)
Togaram2XP_017449897.2 PLN03209 <196..475 CDD:178748
CLASP_N 660..828 CDD:403532 26/147 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166352152
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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