Protein Alignment E23 and AUS1

DIOPT Version :9

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_014654.1
• Gene: AUS1 / 854175
• SGDID: S000005537
• Length: 1394
• Species: Saccharomyces cerevisiae
• Alignment Length: 698
• Identity: 173/698 - (24%)
• Similarity: 287/698 - (41%)
• Gaps: 184/698 - (26%)

  Fly   296 IGKSILVDAKSNSPASLSYHFEKSAAANQQKQHHNINICNSHHPHHHSQNQPQHSLQLTFQNLNV 360
            |.||..|.:.|:|.:::.|....|   |::...::.|    ..|...:....:|.  ::::|:|.
Yeast   703 IPKSHSVSSSSSSLSAVPYQISPS---NKEMALNDYN----EQPITETVETQKHI--ISWKNINY 758

  Fly   361 LHNERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQR---HIDSGSVFLNREPLTKK--W 420
            ....::::::.|||:| ..:.|:||.||:||||||:.|| ||   .:.||.:.::..|||.:  :
Yeast   759 TVGTKKLINNASGFIS-SGLTALMGESGAGKTTLLNVLS-QRVETGVVSGEILIDGHPLTDEDAF 821

  Fly   421 RRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYL 485
            :|.||:|.|:::....|:::|::..:.|||  ....||    .:|.:...|:|.       .|.|
Yeast   822 KRSIGFVQQQDLHLDLLSVKESLEISCLLR--GDGDRA----YLDTVSNLLKLP-------SDIL 873

  Fly   486 NRGLSGGEKKRANIACELLTNP-LLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQP 549
            ...|:..::|..:|..||:|.| ||:.|||||||||:.:|::::|.||:.: |:.:.|..::|||
Yeast   874 VADLNPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALTIVKFLKQLS-LQGQAIFCTIHQP 937

  Fly   550 SSQMFHMFDKLLLLHQ-GRTAYFGDVQNIYRHFEDIGVTI---KPHYNPADFVLEQL-----KSH 605
            |..:...||.:.||.: |...:||.:.:...:|.....|:   |.|.||||||::.:     .:.
Yeast   938 SKSVISHFDNIFLLKRGGECVFFGPMDDACGYFMSHDNTLVYDKEHDNPADFVIDAVGNSNSSAG 1002

  Fly   606 PDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHH 670
            .|..|:...         ||:..|..|...:.||.....||:.
Yeast  1003 KDTAEEALT---------LNKEAIDWSALWESSVEKKLVKKET---------------------- 1036

  Fly   671 QYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPT 735
                       .|:|:|..|                             ||..::..   |....
Yeast  1037 -----------ARLEDDARA-----------------------------SGVDYTTS---LWKQP 1058

  Fly   736 SFHTQFCVLSSRNFREAKPRMLSKLNWFQTIGLALMAGA---IWFQLPRTEEFLHDLQGWMFFSQ 797
            |:..|..:::.|.:...|..|.     :......|..||   |.|.....:..:..||..:||
Yeast  1059 SYLQQLALITRRQYICTKRDMT-----YVMAKYCLNGGAGLFIGFSFWHIKHNIIGLQDSIFF-- 1116

  Fly   798 TYWMLFALFGALNSFPSE----REV-VSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISY 857
            .:..|......:|....:    :|| |::|.||..|..:...|::...||||.:|..|
Yeast  1117 CFMALCVSSPLINQIQDKALKTKEVYVAREARSNTYHWTVLLLSQSIIELPLALTSST------- 1174

  Fly   858 PMLGCTSLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLATQLFGGYLSSRIP 922
                     |||:...|         |.||         |.:...:.::.|...||..|.|:.
Yeast  1175 ---------LFFVCAFF---------SCGF---------NNAGWSAGVFFLNYMLFAAYYSTL-- 1210

  Fly   923 EGLSWIRYTSMIHYAYQNMQ--------ILEFREGAAIGCGSPSSYEI 962
             || |:.||:      .|:|        |..|   .|..||....|.:
Yeast  1211 -GL-WLIYTA------PNLQTAAVFVAFIYSF---TASFCGVMQPYSL 1247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	ABCG_EPDR	350..572	CDD:213180	76/228 (33%)
		3a01204	363..1009	CDD:273361	159/631 (25%)
		ABC2_membrane	744..943	CDD:279410	48/214 (22%)
AUS1	NP_014654.1	3a01205	56..1369	CDD:273362	173/698 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
TreeFam	0	0.000	Not matched by this tool.
	1	1.000