Protein Alignment E23 and YOL075C

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_014567.2
• Gene: YOL075C / 854080
• SGDID: S000005435
• Length: 1294
• Species: Saccharomyces cerevisiae
• Alignment Length: 810
• Identity: 194/810 - (23%)
• Similarity: 351/810 - (43%)
• Gaps: 205/810 - (25%)

  Fly   280 TIPSTDNLTSSNGLANIGKSIL----VD-------------AKSNSPASLS---------YHFEK 318
            |:|:...|..|.|...:|..||    :|             .|..||..:.         || :|
Yeast   602 TVPAVVLLCWSVGYFVVGAIILYLHKIDITLQNEVKSKQKKIKKKSPTGMKPEIQLLDDVYH-QK 665

  Fly   319 SAAANQQKQHHNINICNSHHPHHHSQNQPQHSLQLTFQNLNVL--------------HNERQILS 369
            ...|.:.|   ||:|                :::|...:|.|:              |..::||.
Yeast   666 DLEAEKGK---NIHI----------------TIKLEDIDLRVIFSAPFSNWKEGNFHHETKEILQ 711

  Fly   370 DVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQ-------RHIDSGSVFLNREPLTKKWRRRI-GY 426
            .|:....|..:.||||||||||::||:.:||:       :...|||:..|...:::...:.: .|
Yeast   712 SVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSGSIMFNDIQVSELMFKNVCSY 776

  Fly   427 VLQ-EEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRGLS 490
            |.| ::.....||::||:.|.|.||| ..:..||:|.:.|:::.:|.|..|:....|:...:|:|
Yeast   777 VSQDDDHLLAALTVKETLKYAAALRL-HHLTEAERMERTDNLIRSLGLKHCENNIIGNEFVKGIS 840

  Fly   491 GGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFH 555
            ||||:|..:..:||.:|.::|||||||||||.::.:::::|::..:.:.|||:|::|||.|::|.
Yeast   841 GGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLCREQGKTIIITIHQPRSELFK 905

  Fly   556 MFDKLLLL-HQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSHPDIREKLFIAAKES 619
            .|..:||| ..||||:.|....:..:|.::|.......|.|||.|:.:..:
Yeast   906 RFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYNCPSFTNVADFFLDLISVN-------------- 956

  Fly   620 HGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTSNGCRV 684
                      |.:..|::| |.|:         ::.|::.:.....|      |:|..|.    :
Yeast   957 ----------TQNEQNEIS-SRAR---------VEKILSAWKANMDN------ESLSPTP----I 991

  Fly   685 EEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRNF 749
            .|.::.:|         :|.|:        .||           :::..|.:....:.|...|.|
Yeast   992 SEKQQYSQ---------ESFFT--------EYS-----------EFVRKPANLVLAYIVNVKRQF 1028

  Fly   750 ---REAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFFSQTYWMLF--ALFGAL 809
               |.:...:::::.....:|:..   |::| .|....:. .:...:..:|....|:  .:.|.|
Yeast  1029 TTTRRSFDSLMARIAQIPGLGVIF---ALFF-APVKHNYT-SISNRLGLAQESTALYFVGMLGNL 1088

  Fly   810 NSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLGC---TSLKLFFLM 871
            ..:|:||:...:|.....|.::.::||.|..||||......:|.:  :.:|.|   .:...||..
Yeast  1089 ACYPTERDYFYEEYNDNVYGIAPFFLAYMTLELPLSALASVLYAV--FTVLACGLPRTAGNFFAT 1151

  Fly   872 LIFLLINTIVAQSVGF----------FIGACCMDMNVSITLSALYTLATQLFGGYLS---SRIPE 923
            :....|.|...:::|.          |:..|     :||.||    :.||: .|.:|   ||:.:
Yeast  1152 VYCSFIVTCCGEALGIMTNTFFERPGFVVNC-----ISIILS----IGTQM-SGLMSLGMSRVLK 1206

  Fly   924 GLSWIR---YTSM--IHYAYQNMQILEFREGAAIGCGSPSSYEICKQQSTEFIPYEEILKAQNST 983
            |.:::.   ||||  |::|:.....|...:|.....|:      |     ||....::|.:..
Yeast  1207 GFNYLNPVGYTSMIIINFAFPGNLKLTCEDGGKNSDGT------C-----EFANGHDVLVSYG-- 1258

  Fly   984 SPLWLNTL----ILMMFFLVFRCLGYAVLR 1009
              |..||.    |::...:::|.:.:.:|:
Yeast  1259 --LVRNTQKYLGIIVCVAIIYRLIAFFILK 1286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	169/685 (25%)
YOL075C	NP_014567.2	3a01205	55..1236	CDD:273362	182/743 (24%)