Protein Alignment E23 and abcg2b

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_001034155.1
• Gene: abcg2b / 570453
• ZFINID: ZDB-GENE-050517-36
• Length: 618
• Species: Danio rerio
• Alignment Length: 692
• Identity: 198/692 - (28%)
• Similarity: 315/692 - (45%)
• Gaps: 138/692 - (19%)

  Fly   353 LTFQNLNVLHN-----------ERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQ---RH 403
            ||:||::....           ||.||.:||| :....:.||||.:|||||:|||.::|:   |.
Zfish    28 LTYQNIHYCIRESRGLCCKKAPERDILKNVSG-IMKTGLNAIMGATGSGKTSLLDVMAGRKDPRG 91

  Fly   404 IDSGSVFLNREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLP-ESMPRAEKMRQVDHI 467
            :.||.|.::.:.:|...|....||:|:::....||:||.::::..|||| |....|:|.::|:.|
Zfish    92 LRSGQVLVDNKLVTSDLRLMSAYVVQDDVLMGTLTVRENLLFSGNLRLPREQFSSADKKKKVESI 156

  Fly   468 LEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLK 532
            :|.|.|..|..||.|....||:||||:||.:|..||:|:|.|:.|||||:||||::|.|::.:|.
Zfish   157 IEELGLEDCADTKIGTEFIRGVSGGERKRCSIGMELITSPTLLFLDEPTTGLDSNTANSIIALLH 221

  Fly   533 RYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADF 597
            |.:: ..:||:.|:|||...:|.:||.|.|:|:|.|.|.|.......:|:.:|.......|||||
Zfish   222 RLSR-GGRTIIFSIHQPRYSIFRLFDYLTLMHKGETVYAGPAGKAIDYFQSLGYERDAFNNPADF 285

  Fly   598 VLEQLKSHPDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYN 662
            .|:                            ||   :.:.:.|....|..|:
Zfish   286 FLD----------------------------IT---NGETATSMPTEKSLAE------------- 306

  Fly   663 QRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSAD 727
                        |:..|..|...::|      :.|..         ..||..|.:....|
Zfish   307 ------------LYRESQFCTAVDEE------LKCIT---------GPSDSLSEAKSKAP----- 339

  Fly   728 DDWLSYPTSFHTQFCVLSSR-NFREAKPRMLSKLNWFQTIGLALMAGAIWFQLPRT-EEFLHDLQ 790
                ||.|||..|..|:..| .....:....|.......|..||:.|.:::|:|.| .|.|.:..
Zfish   340 ----SYVTSFSYQLKVVCWRTGLNVVRNPQTSYAQIAMNILFALLIGLVYYQMPLTLPEALQNRI 400

  Fly   791 GWMFFSQTYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAE-LPLVITLPTVYLM 854
            | .||.....|:|....|:..|.:||.:...|...|.||.|.|:|:|:..: ||..|....::..
Zfish   401 G-AFFFLIINMVFGNLSAVELFINERAIFVHENSGGYYRTSVYFLSKVFVDLLPNRIVPILIFSS 464

  Fly   855 ISYPMLG---------CTSLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLAT 910
            |||.|:|         |.:|.:..:.|..:.:..:|:.||..|..|     |:.:.|..::.:
Zfish   465 ISYYMMGLNPAFTSFLCFALTVSLVSLAGVSLAFLVSASVSTFAMA-----NILVVLPFVFMM-- 522

  Fly   911 QLFGGYL--SSRIPEGLSWIRYTSMIHYAYQNMQILEFREGAAIGCGSPSSYEICKQQSTEFIPY 973
             :|||:|  .:.:...|||:::||:..|....:.|.|.: |..:..|:.:            :|.
Zfish   523 -VFGGFLVNLNSMLNWLSWLKWTSIFKYGLDAVTINEMK-GLVLYSGNAT------------LPG 573

  Fly   974 EEILKAQN---STSPLWLNTLILMMFFLVFRCLGYAVLRFLR 1012
            |..|::|.   |....|.|.:.|:...||  |:.:|.::..|
Zfish   574 ELYLESQGIDYSVWGFWQNEVALLGIVLV--CMTFAYIQLRR 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	193/677 (29%)
abcg2b	NP_001034155.1	3a01204	41..616	CDD:273361	194/679 (29%)