Protein Alignment E23 and abcg5

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_001122162.1
• Gene: abcg5 / 557317
• ZFINID: ZDB-GENE-050517-40
• Length: 652
• Species: Danio rerio
• Alignment Length: 595
• Identity: 144/595 - (24%)
• Similarity: 259/595 - (43%)
• Gaps: 93/595 - (15%)

  Fly   365 RQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDS-----GSVFLNREPLTK-KWRRR 423
            ||||::||..:...:::.|:|.||||||||||.::|:  |.:     |.||:|...|.: :::..
Zfish    70 RQILNEVSFHLDSGQIMGILGNSGSGKTTLLDAIAGR--IGNSGNLQGEVFVNGRKLKREQFQDC 132

  Fly   424 IGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRG 488
            ..||||.:.....||:.||:.|||.|.|.:....|.: ::|..::..|.||....:..|..:..|
Zfish   133 FSYVLQSDNLLSYLTVEETLTYTAQLALRKHSAEAIR-KKVTAVMAELSLGHVAHSVIGGRVFPG 196

  Fly   489 LSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQM 553
            :||||::|.:||.:||.:|.::||||||:||||.:|..::.:|...|: ..:.:::::|||.|::
Zfish   197 ISGGERRRVSIASQLLQDPKVILLDEPTTGLDSMTANQIVMLLAELAR-RDRIVIVTIHQPRSEL 260

  Fly   554 FHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSHPDIREKLFIAAKE 618
            |.:|:::.::.||...:.|:...:...|...|.....:.||.|..::  .:..|.|     .::.
Zfish   261 FRIFNRIAIMSQGELVFCGEPHKMVDFFSSCGYECPEYCNPFDIYVD--LTSVDTR-----CSER 318

  Fly   619 SHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTSNGCR 683
            ....|...:.|||::.|.                                 ..|.|:.
Zfish   319 EAATYRRMHDITSAYQNS---------------------------------EIYTNMQ------- 343

  Fly   684 VEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRN 748
             |:.|::.|.    .......|.|..|.:|.|                        :..||..|.
Zfish   344 -EKIEQSCQR----PDKPMIPFKSKESPNCIS------------------------KLGVLLRRT 379

  Fly   749 FRE-AKPRMLSKLNWFQTIGLALMAGAIWFQLPR--TEEFLHDLQGWMFFSQTYWMLFALFGALN 810
            ||. ::.||...:...|.:...|.......:|.:  |:..:.|..|.::.|........:..|:.
Zfish   380 FRNVSRDRMGILMRLSQNLIYGLFIAFFLMRLGKDVTKGAVQDRIGLIYQSMGASPYTGMLNAVA 444

  Fly   811 SFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLGCTSLKLFFLML-IF 874
            .||:.|.:..:|.:.|.|:....:||.:...||..|....::....|..:|.....:.||.. ..
Zfish   445 LFPALRAISDQESKDGLYQKWQMFLAYIIHILPFSIISVFIFASFLYWTVGMNPDPVRFLCFSAV 509

  Fly   875 LLINTIVAQSVGFFIGACCMDMNVSITLSALYTLATQLFG-GYLS--SRIPEGLSWIRYTSMIHY 936
            :::..|:.:.:...:.....|.|:..:..||..:|..:.| |:|.  .::|....|:.|.:...|
Zfish   510 VMVPHIIGELLTLVLLGVVQDPNMVNSGVALLNIAGIMVGSGFLRGFKQMPVVFQWLSYLTFQKY 574

  Fly   937 AYQNMQILEF 946
            ..:.:.:.||
Zfish   575 GCELLIVTEF 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	144/595 (24%)
abcg5	NP_001122162.1	3a01204	50..645	CDD:273361	144/595 (24%)
		ABCG_White	53..279	CDD:213201	76/212 (36%)