Protein Alignment E23 and abcg1

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_001103924.1
• Gene: abcg1 / 556979
• ZFINID: ZDB-GENE-070424-84
• Length: 673
• Species: Danio rerio
• Alignment Length: 761
• Identity: 212/761 - (27%)
• Similarity: 355/761 - (46%)
• Gaps: 135/761 - (17%)

  Fly   283 STDNLTSSNGL---ANIGKSILVDAKS---NSPASLSYHFEKSAA----ANQQKQHHNINICN-- 335
            |.:|.|.:|.:   .|....:::|.::   :....:|.|......    |:.:|..:|:....
Zfish     9 SFNNTTVTNSIIMNTNGPPDLMLDPRTVCVSIDEMMSNHVSSQQTPLLHAHLKKVENNLTEAQRF 73

  Fly   336 SHHPHHHSQNQPQHSLQLTFQNLNVLHNE---------RQILSDVSGFVSPCEVLAIMGPSGSGK 391
            |:.|...:.|       :.|::|:....|         :.:|..:||..:...::|||||||:||
Zfish    74 SYLPRRPAVN-------IEFKDLSYSVPEGPWWRKKGYKTLLKGISGNFTGGALVAIMGPSGAGK 131

  Fly   392 TTLLDCLSGQRHID-SGSVFLNREPLTKKWRRRIG-YVLQEEIFFPQLTLRETVVYTALLRLPE- 453
            :||::.|:|.|... .|.:.:|..|...:..|::. |::|:::..|.||::|.::.:|.|:|.|
Zfish   132 STLMNILAGYRETGMKGEILINGHPRDLRSFRKVSCYIMQDDMLLPHLTVQEAMMVSANLKLQEK 196

  Fly   454 SMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSG 518
            ...|.|.:|:   ||.||.|..|.:|:     ...||||::||..||.||:.||.:|..||||||
Zfish   197 DEGRREMVRE---ILTALGLLECAKTR-----TSHLSGGQRKRLAIALELVNNPPVMFFDEPTSG 253

  Fly   519 LDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFED 583
            |||.|...::.::|..|| ..:|::.::||||:::|.:||||.:|.||:..|.|.|.::..:..|
Zfish   254 LDSSSCFQVVSLMKALAQ-GGRTVICTIHQPSAKVFELFDKLYVLSQGQCIYRGKVSSLIPYLRD 317

  Fly   584 IGVTIKPHYNPADFVLEQLKSHPDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQA 648
            :|::...::|||||::|              .|...:|:...|.......|        |.:|
Zfish   318 LGLSCPTYHNPADFIME--------------VASGEYGDQTARLVKAVQEH--------KCEK-- 358

  Fly   649 DSILIDDIINNYYNQRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDC 713
                      :|..:.:....|.....|..|       |||                 |.:|..|
Zfish   359 ----------DYKTEMNGNGVHNPFLWHRPS-------DEE-----------------SSSSEGC 389

  Fly   714 HSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRNFRE-AKPRMLSKLNWFQTIGLALMAGAIWF 777
            ||:||                 |..||||:|..|.|.. .:..:|:.|.....:|:.::.|.::.
Zfish   390 HSFSA-----------------SCLTQFCILFKRTFLSIMRDSVLTHLRIMSHLGIGILIGLLYL 437

  Fly   778 QLPRTEEFLHDLQGWMFFSQTYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAEL 842
            .:....:.:....|::|||..:.|..||...:.:||.|..|..:|..:..|.|.||||||..|::
Zfish   438 GIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADV 502

  Fly   843 PLVITLPTVYLMISYPMLGCTSLKLFFLMLIFL-LINTIVAQSVGFFIGACCMDMNVSITLSALY 906
            |..|..|..|..|.|.|....|..:.|::.:.| .:.::||||:|..|||....:.|:..:..:.
Zfish   503 PFQIVFPVAYCSIVYWMTSQPSDAVRFILFLALGTLTSLVAQSLGLLIGAASTSLQVATFVGPVT 567

  Fly   907 TLATQLFGGYLSS--RIPEGLSWIRYTSMIHYAYQNMQILEF----REGAAIGCGSPSSYEICKQ 965
            .:...||.|:..|  .||:.|.||.|.|.:.|.::.: ||..    ||.  :.|.        |.
Zfish   568 AIPVLLFSGFFVSFDTIPKYLQWISYISYVRYGFEGV-ILSIYGLDRED--LHCD--------KD 621

  Fly   966 QSTEFIPYEEILKAQN-STSPLWLNTLILMMFFLVFRCLGYAVLRF 1010
            ::..|...|.|||..: ..:.|:::.::|.:||:..|.:.|.|||:
Zfish   622 ETCHFQKSEAILKELDVEDAKLYMDFIVLGIFFISLRLIAYFVLRY 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	194/666 (29%)
abcg1	NP_001103924.1	3a01204	67..673	CDD:273361	201/703 (29%)