Protein Alignment E23 and Abcg3

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: XP_038948191.1
• Gene: Abcg3 / 498327
• RGDID: 1565568
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 777
• Identity: 187/777 - (24%)
• Similarity: 327/777 - (42%)
• Gaps: 146/777 - (18%)

  Fly   277 SQTTIPSTDNLTSSNGLA-------NIGKSILVDAKSNSPASLSYHFEKSAAANQQKQHHNINIC 334
            |:|:||...  .|||.::       || |..|::.....|..:|.:.:.......:::|.::...
  Rat     7 SKTSIPWKG--VSSNCVSIHRSTYKNI-KPTLINPLKEEPLKMSSNNDPIVIPMAERRHSDLPET 68

  Fly   335 NSHHPHHHSQNQPQHSLQLTFQNLNV---------LHNERQI---LSDVSGFVSPCEVLAIMGPS 387
            |:..|...::     ...|:|.|::.         |..:.::   ||.:||.:.| .:.|||||.
  Rat    69 NTSDPETLTK-----EAVLSFHNISYRETVQSGFPLRQQTRVIERLSSISGIMGP-GLNAIMGPQ 127

  Fly   388 GSGKTTLLDCLSGQRHID--SGSVFLNREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLR 450
            ...::.|||.|:.:|...  ||.:.:|.:|....::...|||.|.::....:|:|:.:.::|.||
  Rat   128 DGSRSLLLDVLAARRDPSGLSGDILVNGKPRPANFKCTSGYVPQNDVVMHTVTVRDNLEFSAALR 192

  Fly   451 LPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEP 515
            ||.::.|.||.|:::.:||.|.|...|.||       ..|...:||.:||.||:....::.||:|
  Rat   193 LPMTITRDEKRRRINEVLELLHLDKEQNTK-------PRSKELRKRTSIAVELIAEHPILFLDDP 250

  Fly   516 TSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRH 580
            |:.||..:...::.||:|.: ::.|||:.|::||...:|..||.|.|:..|:..:.|..::...:
  Rat   251 TTDLDLTTTTYVISVLRRMS-MKGKTIIFSINQPQYSIFRFFDSLTLVASGKLMFHGPARDALEY 314

  Fly   581 FEDIGVTIKPHYNPADFVLEQLKSHPDIREKLFIAAKESH--GNYLNRNCITSSHHNQVSVSGAK 643
            |...|...:.|.|||||.|:.      |...|....::.|  |||
  Rat   315 FTSAGYQYESHNNPADFFLDV------INGGLCDTEEDGHEAGNY-------------------- 353

  Fly   644 GKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTSNGCRVEE-------DEEAAQHLVWCAADS 701
                      :::....|.......:...::..|:....|:::       |..:|..
  Rat   354 ----------EELFERKYQATKKLANMYAQSRLHSDTRARLDQLLGQQQLDRNSAVE-------- 400

  Fly   702 QSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRNFR-----EAKPRMLSKLN 761
                ::|.:...|...            |::|.          |.:|.|     .||..::
  Rat   401 ----TTCVTPFWHQLM------------WITYQ----------SFKNIRGFLLVTAKQAVI---- 435

  Fly   762 WFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFFSQTYWMLFALFGALNSFPSEREVVSKERRSG 826
               |..||.:.| |.||:.:.......::..:.:..|.:.......|...|..:|:....|..||
  Rat   436 ---TATLAALVG-IAFQILKNGCIEVYIRAGLLYLLTIFQCITSVSAGELFVIDRDRFLHEHTSG 496

  Fly   827 AYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLGC-TSLKLFFLMLIFLLINTIVAQSVGFFIG 890
            .||:|:|:..|:.|||.....||:..::|:|.:.|. ||:..||.||..:::....|.|:...||
  Rat   497 YYRVSSYFFGKLLAELIPRRLLPSTIVLITYFIAGVKTSMSSFFAMLFTVMMLAYSASSLPLSIG 561

  Fly   891 ACCMDMNVSITLSALYTLATQLFGG---YLSSRIPEGLSWIRYTSMIHYAYQNMQILEFREGAAI 952
            |....:.|......:|.:....|.|   |..|.:|: ||||:|.::.||.::.:...||     :
  Rat   562 AGENAVAVPTLFVTIYFVFMLFFSGLSLYSGSLLPQ-LSWIQYFNIPHYGFKALLHNEF-----L 620

  Fly   953 G---CGSPSSYEICKQQSTEFIPYEEILKAQN---STSPLWLNTLILMMFFLVFRCLGYAVL 1008
            |   |...:..|:.:..:......||.|..|.   |:...|.|.|.|....::...:.|..|
  Rat   621 GQNFCSEHNIEEVSRCHNYVICTGEEFLTIQGIDLSSWGFWENHLALACIMIILLTITYVQL 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	167/675 (25%)
Abcg3	XP_038948191.1	3a01204	109..683	CDD:273361	167/667 (25%)