Protein Alignment E23 and CG9663

DIOPT Version :9

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_608760.2
• Gene: CG9663 / 33541
• FlyBaseID: FBgn0031516
• Length: 808
• Species: Drosophila melanogaster
• Alignment Length: 876
• Identity: 218/876 - (24%)
• Similarity: 375/876 - (42%)
• Gaps: 175/876 - (19%)

  Fly   230 ASVASPPATSDATAATSVASSD----SSASSSASSTSSSSSSSTSSEFTHTSQTTIPS------- 283
            ||..||          :|...|    :...||:.:...|..|.|.|.......|.:||
  Fly     7 ASAVSP----------NVTGGDVIRLNHLKSSSETHLPSRGSGTGSGALPRPTTPVPSKKLSSKR 61

  Fly   284 ----TDNLTSSN---GLANIGKSILVDAKS-----------NSPASLSYHFEKSAAANQQKQHHN 330
                |.|:.:.:   .||....::|..::|           :|||:.|   ::|.|:....:..|
  Fly    62 PPHLTLNIKAKSHDAPLAETENTVLSTSESVYGTPLGATPVSSPANQS---QRSQASQHSDESRN 123

  Fly   331 INIC----NSHHPHHHSQNQPQHSLQLTFQNL------NVLHNE-RQILSDVSGFVSPCEVLAIM 384
            .:..    .|..|  |.|.:....:.:.|:|:      .|...| :.:|..::|:....|:.|::
  Fly   124 TSSTATSGGSIFP--HEQYKTIKKINIGFENIRYTTKFGVFQRETKDVLMGLTGYFKSGELSAVI 186

  Fly   385 GPSGSGKTTLLDCLSGQRHIDSGSVFL---NREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYT 446
            ||||:||:|||:.|||.........|.   ||..| |.::..:.::.|:......|:::|.:.:.
  Fly   187 GPSGAGKSTLLNILSGYTTYGFTGDFRVNGNRRDL-KAFKSNVAFIRQDTSLQAFLSVKEAMHFA 250

  Fly   447 ALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLML 511
            |.|::...|..:||..:|..||||:.:...:.|:.|.     ||||:|||..||.||:.||.:::
  Fly   251 ANLKIGTHMTHSEKRERVKCILEAIGMYENRHTRTGQ-----LSGGQKKRLAIALELVNNPPVLI 310

  Fly   512 LDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQN 576
            |||||:||||.::..|:.:||:.| :|.:|::.::||||:..|.|||.|..:.:|:..|.|..||
  Fly   311 LDEPTTGLDSFTSNQLINLLKKLA-IEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAGGAQN 374

  Fly   577 IYRHFEDIGVTIKPHYNPADFVLEQLKSH-----PDIREKLFIAAKESHGNYLNRNCITSSHHNQ 636
            :......:.:.....|||||:::| :.:|     .|.:.:..:|..::..|...|...|:
  Fly   375 LLPFLGALNLHCPESYNPADYLME-IATHDYDTAEDNQLEKLVALMDNGRNEDYRQSKTA----- 433

  Fly   637 VSVSGAKGKKQADSILIDDII-------------------NNY-----YNQRSNRHHHQYENLHH 677
             .|:.....|:.|.::...:|                   |.:     .|:.|:|
  Fly   434 -RVAQLAAMKKVDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKPLTPINELSSR---------- 487

  Fly   678 TSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAG-SGPGHSADDDWLS-----YPTS 736
                             ||   |||:.....|.|.|...... |.|....|...|.     |.|.
  Fly   488 -----------------VW---DSQTAGIGNAGSCCKPKKKNKSRPAIELDPSHLCKRQNIYATP 532

  Fly   737 FHTQFCVLSSRNF----REAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFFSQ 797
            |:.|..:|..|.|    |::.   |:.:.:...:...::.|.::|.:........::..::|::.
  Fly   533 FYRQLSILLVRTFLLIWRDSS---LTTMRFAIHLITGILIGTLYFGIGNDAAQTLNIFRYLFYTI 594

  Fly   798 TYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVI------TLPTVYLMIS 856
            .:.|..|..|.|..||.|..:||:|..:..|.|.|||:|...|:||:.|      .:|| |||..
  Fly   595 MFIMYCAFSGILVKFPLEFPIVSREHFNRWYSLRAYYVAITLADLPIQIICSALFIVPT-YLMTQ 658

  Fly   857 YPMLGCTSLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLATQLFGGY--LSS 919
            .|:    .|..|.:..:.:.:..:|:||:|..:|| .:.:.:...|...:......|.|:  :..
  Fly   659 QPL----ELWRFGMFFLIVFVTALVSQSIGLAVGA-ALSLKLGSILGPFFICPFLQFSGFFLMEK 718

  Fly   920 RIPEGLSWIRYTSMIHYAYQNMQILEF---REGAAIGCGSPSSYEI-CKQQSTEFIPYEEILKAQ 980
            ..|..|.|:...|.:.|:.:...:..|   ||  .:.|.     |: |..:..:|     |||:.
  Fly   719 DAPVFLRWMFDISFLKYSLEGATMAIFGYDRE--PLACN-----ELYCHLRHPQF-----ILKSL 771

  Fly   981 NSTSPLWLNTLILMMFFLVF-RCLGYAVLRF 1010
            :..:..:...||.:...||| |.|.:.::.|
  Fly   772 DMANGNYTLALIFLFGVLVFLRILAFYIMSF 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	ABCG_EPDR	350..572	CDD:213180	79/231 (34%)
		3a01204	363..1009	CDD:273361	182/701 (26%)
		ABC2_membrane	744..943	CDD:279410	50/210 (24%)
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	79/231 (34%)
		3a01204	149..808	CDD:273361	186/719 (26%)
		ABC2_membrane	540..743	CDD:279410	50/211 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I3665
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	8	7.820