Protein Alignment E23 and CG4822

DIOPT Version :9

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Alignment Length: 686
• Identity: 173/686 - (25%)
• Similarity: 294/686 - (42%)
• Gaps: 152/686 - (22%)

  Fly   365 RQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHI-DSGSVFLNREPLTKK-WRRRIGYV 427
            :.||..|:|.....|:.||:||||:||||||:.|:|...: :||.:.:|..|...: :|:...|:
  Fly    73 KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCESGEILVNNSPRDMRVFRKMSRYI 137

  Fly   428 LQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLN---RGL 489
            :|.::...|.|:.|.::..|.|:|.:.:...:|:..:|.||..|.|        .|.||   :.|
  Fly   138 MQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRL--------KDTLNTMAQKL 194

  Fly   490 SGGEKKRANIACELLTNPLLMLLDEPTSGLD---SHSAISLMKVLKRYAQLEQKTIVISVHQPSS 551
            ||||:||..||.||:.||.::.|||||:|||   |...|:|:|||....    :|::.|:|.||:
  Fly   195 SGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGG----RTVICSIHTPSA 255

  Fly   552 QMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSHPDIREKLFIAA 616
            ::|.|.|.:.:|.:|:..|.|...||....::.|:.....||||||::|             :|.
  Fly   256 KIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIE-------------VAC 307

  Fly   617 KESHGNYLNRNCITSSHHNQVSVSG-----------AKGKKQADSILIDDIINNYYNQRSNRHHH 670
            .|..|:|         |...|...|           .:|:............:::|.
  Fly   308 LEYGGSY---------HEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSFYE-------- 355

  Fly   671 QYENLHHTSNGCRVEEDEEAAQHLV-----WCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDW 730
                        |.:.|||.:..|:     |                                 |
  Fly   356 ------------RDQFDEEISPKLLEAKCSW---------------------------------W 375

  Fly   731 LSYPTSFHTQFCVLSSRNFREAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFF 795
            |.|.       .:|.....:..:.:...||.::..|.|||:.|:::|.:..:........|:||.
  Fly   376 LQYK-------LLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFT 433

  Fly   796 SQTYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPML 860
            ....::...:...|..||:|..::.:|..:..||||:||.|.:.::||.:..|..:||.|.| ::
  Fly   434 IVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVY-LM 497

  Fly   861 GCTSLKLFFLMLIFLL--INTIVAQSVGFFIGACCMDMN---------VSITLSALYTLATQLFG 914
            ....|:.|...::|.:  :..:.:.|.|..|.:....:|         |.:.|.::|.:.   :|
  Fly   498 SSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRLSLVNAMFMGPVLAVPLILLSIYGIG---YG 559

  Fly   915 G--YLS--SRIPEGLSWIRYT--SMIHYAYQNMQILEFREGAAIGCGSPSSYEICKQQSTEFIPY 973
            |  |:|  .|....||::|::  .::...|...:.....|...|.|....|..:     ..|:.:
  Fly   560 GGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVL-----LAFLGF 619

  Fly   974 EEILKAQNSTSPLWLNTLILMMFFLVFRCLGYAVLR 1009
            |.:       ..|| :...||.|:|:|....|.::|
  Fly   620 ENM-------HYLW-SLSCLMSFYLLFTVAAYFMIR 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	ABCG_EPDR	350..572	CDD:213180	79/214 (37%)
		3a01204	363..1009	CDD:273361	172/684 (25%)
		ABC2_membrane	744..943	CDD:279410	50/215 (23%)
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	79/214 (37%)
		3a01204	67..654	CDD:273361	173/686 (25%)
		ABC2_membrane	381..587	CDD:279410	49/209 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	6	5.920