Protein Alignment E23 and Abcg3l1

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_001004076.2
• Gene: Abcg3l1 / 289453
• RGDID: 1303294
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 698
• Identity: 176/698 - (25%)
• Similarity: 301/698 - (43%)
• Gaps: 131/698 - (18%)

  Fly   353 LTFQNLNV---------LHNERQI---LSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHID 405
            |:|.|::.         |..:.::   ||.:||.:.| .:.|||||....::.|||.|:.:|  |
  Rat    37 LSFHNISYRETVQSGFPLRQQTRVMERLSSISGIMGP-GLNAIMGPQDGSRSLLLDVLAARR--D 98

  Fly   406 ----SGSVFLNREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDH 466
                ||.:.:|.:|....::...||:.|.::....:|:|:.:.::|.||||.::.|.||.|:::.
  Rat    99 PCGLSGDILINGKPRPANFKCTSGYIPQNDVVLGTVTVRDNLEFSAALRLPMTVTRDEKRRRINE 163

  Fly   467 ILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVL 531
            :||.|.|...|..|       ..|.|.:||.:||.||:|...::.||:||:|||..:...::.:|
  Rat   164 VLELLHLEKEQNVK-------PRSKGLRKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVISIL 221

  Fly   532 KRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPAD 596
            :|.: ::.|||:.|::||...:|..||.|.|:..|:..:.|..::...:|...|...:.|.||||
  Rat   222 RRMS-MKGKTIIFSINQPQYSIFRFFDSLTLVASGKLMFHGPARDALEYFTSAGYQYESHNNPAD 285

  Fly   597 FVLEQLK-SHPDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNY 660
            |.|:.:. ..||..|       :.|....|...:...|    .|:|......|.|.|
  Rat   286 FFLDVINGGFPDTEE-------DGHEADENEEFVERQH----QVTGKLANMYAQSPL-------- 331

  Fly   661 YNQRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHS 725
                            |::...|:::          ...:.:.:.||...:.|
  Rat   332 ----------------HSATRARLDQ----------LLGEQKLDRSSAVETTC------------ 358

  Fly   726 ADDDWLSYPTSFHTQFCVLSSRNFREAKPRMLSKLNWFQTIG------LALMAGAIWFQLPRTEE 784
                    .|.|..|...::.|:|:.     .....|..||.      ||::.|.. |:|  .:.
  Rat   359 --------VTPFWHQLGWITRRSFKN-----FLGFPWVTTIQVIIIVILAVVVGTA-FRL--LQN 407

  Fly   785 FLHDLQGWMFFSQTYWMLFALFGALNS------FPSEREVVSKERRSGAYRLSAYYLAKMCAEL- 842
            ...:||    ......:|...|..:.|      |..:::....|..||.||:|:|:..|:.|||
  Rat   408 VCTELQ----MRAILILLLTGFQCITSVTAGELFVIDQDRFLHEHTSGYYRVSSYFFGKLLAELI 468

  Fly   843 PLVITLPTVYLMISYPMLGC-TSLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALY 906
            |..:...|::.:|:|.:.|. ||::.||.|...:::....|.|:...:||......::..|..:|
  Rat   469 PRRLLPSTIFTLITYFIAGLRTSVRGFFTMTFTIMMLAYSASSLSLSLGAGENVAAITTLLVTIY 533

  Fly   907 TLATQLFGGY-LSSRIPEGLSWIRYTSMIHYAYQNMQILEFREGAAIG---CGSPSSYEICKQQS 967
            .:....|.|. |.:.....||||||.|:.||.::.:...||     :|   |...::.|:.:.|:
  Rat   534 FVFMLFFSGLSLDTGFLPVLSWIRYFSIPHYGFRALLHNEF-----LGQNFCPEYNTEEVSRCQN 593

  Fly   968 TEFIPYEEILKAQN---STSPLWLNTLILMMFFLVFRCLGYAVLRFLR 1012
            ......||.|:.|.   |:...|.|.|.|....::...:.|..|..|:
  Rat   594 YVICTGEEFLEIQGFHLSSWGFWENHLALACTMIILLTITYVQLLLLK 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	170/674 (25%)
Abcg3l1	NP_001004076.2	3a01204	64..644	CDD:273361	172/671 (26%)