Protein Alignment E23 and Abcg3

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: XP_017176394.1
• Gene: Abcg3 / 27405
• MGIID: 1351624
• Length: 683
• Species: Mus musculus
• Alignment Length: 814
• Identity: 196/814 - (24%)
• Similarity: 329/814 - (40%)
• Gaps: 196/814 - (24%)

  Fly   217 PATSAVAAAAAAAASVASPPATSDATAATSVA---------SSDSSASSSASSTSSSSS--SSTS 270
            |...:....|.::|....|....|...:.|.|         |.|.|..||.:|::.|..  |...
Mouse     4 PTLPSAPLPATSSALFGFPAPDHDHRGSKSSAEQKPEPLAPSKDPSCKSSCASSNLSPCIISQWK 68

  Fly   271 SEFTHTSQTTIPSTDNLTSSNGLANIGKSILVDAKS-NSPASLSYHFEKSAAANQQKQHHNINIC 334
            .|....:....|:..::...: |.::.::...|.|: ...|.||:|                ||
Mouse    69 KEPPEMASNNDPTVISMIERH-LCDLPETNTSDLKTLTEEAVLSFH----------------NI- 115

  Fly   335 NSHHPHHHSQNQPQHSLQLTFQNLNVLHNERQI---LSDVSGFVSPCEVLAIMGPSGSGKTTLLD 396
                           |.|.|.|:...|..:..:   ||::||.:.| .:.|||||....::.|||
Mouse   116 ---------------SYQETVQSGFPLRKKAYVIERLSNISGIMKP-GLNAIMGPQDGSRSLLLD 164

  Fly   397 CLSGQRHID----SGSVFLNREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPR 457
            .|:.:|  |    ||.:.:|.:|....::...|||.|.::....:|:|:.:.::|.||||.::.|
Mouse   165 VLAARR--DPRGLSGDILINGKPRPANFKCTSGYVPQNDVVLGTVTVRDNLEFSAALRLPVTITR 227

  Fly   458 AEKMRQVDHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSH 522
            .||.|:::.:||.|.|...|..|       ..|...:||.:||.||:|...::.||:||:|||..
Mouse   228 DEKRRRINEVLELLHLNKEQNIK-------PRSKELRKRTSIAMELVTEHPILFLDDPTTGLDLR 285

  Fly   523 SAISLMKVLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVT 587
            :...::.||:|.:: :.:||:.|::||...:|..||.|.|:..|:..:.|..|:...:|...|..
Mouse   286 TTTDVILVLRRMSK-KGRTIIFSINQPQYSIFKFFDSLTLVASGKVMFHGPAQDALEYFRSAGYN 349

  Fly   588 IKPHYNPADFVLEQLK------------SHPDIR-EKLFIAAKESHGNYLNRNCITSSHHNQVSV 639
            .:.|.|||||.|:.:.            .|.|.: |:||                    ..|..|
Mouse   350 YESHNNPADFFLDVINGGFSNILDTEEDGHEDDKYEELF--------------------ERQYQV 394

  Fly   640 SGAKGKKQADS-------ILIDDIINNYYNQRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWC 697
            :|......|.|       .::|.::.....:||:                .||
Mouse   395 TGKLANMYAQSPLYSETRAILDQLLGEQKLERSS----------------AVE------------ 431

  Fly   698 AADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRNFREAKPRMLSKLNW 762
                    ::|.:..||...            |:         .| .|.:||:        ...|
Mouse   432 --------TTCVTPFCHQLK------------WI---------IC-QSFKNFK--------GFPW 458

  Fly   763 ---FQTIGLALMAGAIW--FQLPRTEEFLHDLQGWMFFSQTYWMLFALFGALNSFPSEREVVSKE 822
               .|.|...::|.|:.  |::.:.:.....::..:.:..|.:.......|...|..:|.....|
Mouse   459 VTVIQAIITVILATAVGTAFRVLKNDCIEVQMRAGLLYLLTIFQCITSVSAGELFVIDRVRFLHE 523

  Fly   823 RRSGAYRLSAYYLAKMCAEL-PLVITLPTVYLMISYPMLGC-TSLKLFFLMLIFLLINTIVAQSV 885
            ..||.||:|:|:..|:.||| |..:...||:.:|:|.:.|. .|:|.||.|:..:::....|.|:
Mouse   524 HTSGYYRVSSYFFGKLLAELIPRRLLPSTVFSLITYVIAGVKMSMKCFFTMICTIMVLAYSASSL 588

  Fly   886 GFFIGACCMDMNVSITLSALYTLATQLFGG---YLSSRIPEGLSWIRYTSMIHYAYQNMQILEFR 947
            ...|||....:.|...|..:|.:....|.|   |..|.:|: ||||:|.|:.||.::.:...||
Mouse   589 PLSIGAGENAVAVPTLLVTIYFVFMLFFSGLSLYSGSFLPK-LSWIQYFSIPHYGFRALLHNEF- 651

  Fly   948 EGAAIGCGSPSSYEICKQQSTEFIPYEEILKAQN 981
                :|      ...|.:.:|     ||:.:..|
Mouse   652 ----LG------QNFCPEHNT-----EEVSRCHN 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	165/656 (25%)
Abcg3	XP_017176394.1	3a01204	137..670	CDD:273361	164/646 (25%)