DRSC/TRiP Functional Genomics Resources

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Protein Alignment E23 and Abca7

DIOPT Version :9

Sequence 1:NP_524648.3 Gene:E23 / 43895 FlyBaseID:FBgn0020445 Length:1017 Species:Drosophila melanogaster
Sequence 2:NP_001334010.1 Gene:Abca7 / 27403 MGIID:1351646 Length:2167 Species:Mus musculus


Alignment Length:325 Identity:80/325 - (24%)
Similarity:128/325 - (39%) Gaps:74/325 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   342 HSQNQPQHSLQLTFQNLNVLHNERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDS 406
            |.:..||.:|    |.||:...|..|             .|.:|.:|:||||.|..|||.....|
Mouse   812 HFRGCPQPAL----QGLNLDFYEGHI-------------TAFLGHNGAGKTTTLSILSGLFPPSS 859

  Fly   407 GSV-FLNREPLTK--KWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESM---PRAEKM-RQV 464
            ||. .|..:..|.  ..|..:|...|..:.|..||:.|.|.:...|:...:.   |..|:: |.|
Mouse   860 GSASILGHDVQTNMAAIRPHLGICPQYNVLFDMLTVEEHVWFYGRLKGVSAAAMGPERERLIRDV 924

  Fly   465 DHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMK 529
            ...|:.            |...|.||||.:::.::|...:....::::||||:|:|..|...:.:
Mouse   925 GLTLKR------------DTQTRHLSGGMQRKLSVAIAFVGGSRVVIMDEPTAGVDPASRRGIWE 977

  Fly   530 VLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNP 594
            :|.:|.  |.:|:::|.|....... :.|::.::..|.....|....:.||   :|         
Mouse   978 LLLKYR--EGRTLILSTHHLDEAEL-LGDRVAMVAGGSLCCCGSPLFLRRH---LG--------- 1027

  Fly   595 ADFVLEQLKSHPDI-------------REKLFIAAKESHGNYLNRNCI----TSSHHNQVSVSGA 642
            ..:.|..:||...:             ||      |:|.||....:..    ||...||....||
Mouse  1028 CGYYLTLVKSSQSLVTHDAKGDSEDPRRE------KKSDGNGRTSDTAFTRGTSDKSNQAPAPGA 1086

  Fly   643  642
            Mouse  1087  1086

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E23NP_524648.3 ABCG_EPDR 350..572 CDD:213180 58/228 (25%)
3a01204 363..1009 CDD:273361 73/304 (24%)
ABC2_membrane 744..943 CDD:279410
Abca7NP_001334010.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1042..1088 12/51 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1172..1192
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2126..2167
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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