Protein Alignment E23 and pdr1

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_593995.1
• Gene: pdr1 / 2543363
• PomBaseID: SPAPB24D3.09C
• Length: 1396
• Species: Schizosaccharomyces pombe
• Alignment Length: 812
• Identity: 183/812 - (22%)
• Similarity: 315/812 - (38%)
• Gaps: 216/812 - (26%)

  Fly   260 STSSSSSSSTSSEFTHTSQTTIPSTDNLTSSNGLANIGKSILVDAKSNSPAS-LSYHFEKSAAAN 323
            :|:..:.:|..|.:.:.........|.|..:.|:. :|.:|.:.|.|...|: :.|..|......
pombe   648 ATAGRTGTSIVSGYQYLQVVYQYKADFLWRNCGII-LGFAIFILASSLILANFIRYDRESVHIPE 711

  Fly   324 QQKQHHNINICNSH--HPHHH--SQNQPQH-------------SLQLTFQNLN----VLHNERQI 367
            .||:.....:.:|.  .|...  ||.:|.:             :|.|.:::||    ...:::||
pombe   712 FQKRKSYSQVASSFLIEPQDKPPSQTEPDNKKVDVSTTLSTNDNLVLCWRDLNFTVVTKTSKKQI 776

  Fly   368 LSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHID---SGSVFLNREPLTKKWRRRIGYVLQ 429
            |::|||::....:.|::|.:.|||:.||..|| ||.|.   .|.:.|:.....|..|:|||||.:
pombe   777 LTNVSGYLKKNTLTALLGENKSGKSVLLRILS-QRGIAGSVEGEITLSGLKNPKNLRKRIGYVRK 840

  Fly   430 EEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRGLSGGEK 494
            ..:|..:.|:|||:...|.||..:....:|:...|:::::.|.||.......|| :.:|||...|
pombe   841 NPLFISEYTVRETLRLHAALRQSKQRSLSEQYAYVEYVIDFLGLGEVADFIVGD-MGKGLSLYHK 904

  Fly   495 KRANIACELLTNP-LLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFHMFD 558
            :..:||.||...| .::|||||.:||||.||..|:.:|::.|: ...:|:.||.||||::..:||
pombe   905 RLLSIAVELSARPGSILLLDEPANGLDSQSAWMLVCILQKLAR-SGLSILCSVSQPSSRILELFD 968

  Fly   559 KLLLLH-QGRTAYFG----DVQNIYRHFEDIGVTIKPHYNPADFVL---EQLKSHPDIREKLFIA 615
            .:|:|. .|.|.|:.    |:..:..:|:.|..|.:...:.|||||   :.||..|:.
pombe   969 MMLILDLNGNTVYYDTMGRDLSKLVNYFKRIHGTNEHSKDTADFVLHCIQFLKQGPEF------- 1026

  Fly   616 AKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTSN 680
                  :|......|::|            ||    :|:.:  |:
pombe  1027 ------DYAGAWASTNTH------------KQ----IIEHV--NF-------------------- 1047

  Fly   681 GCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDW---LSYPTSFHTQFC 742
               :.::.|.                                   .|||:   ..:.|||..|..
pombe  1048 ---IMDNPEL-----------------------------------TDDDFPNETRFMTSFFFQIY 1074

  Fly   743 VLSSRNFREAKPRMLSKLNWFQTIGLALMAG-AIWFQLPRTEEFLHDLQGWMFFSQTYWMLFALF 806
            .:|.||| .|..|..|.|.  ..:...::|| .|.|...:....:.:.|..||  ..|.:..|..
pombe  1075 KISMRNF-VAYWRDSSLLR--ARVAFNIVAGLIIGFSFYKQGVGVEETQNKMF--SAYMLTVAST 1134

  Fly   807 GALNSFPSE----REVVSK-ERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISY--------- 857
            ..:|....:    |.:..: |:.:..|..:|:.:|....|..:.....|::....|
pombe  1135 STMNGLQPKFIYFRSIYEQYEQNTAIYSRTAFIIAFFLVEAVINCCFATLFFFGWYYPSGFYEFN 1199

  Fly   858 ---PMLGCTSLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLATQLFGGYLSS 919
               |..|..:   :.:::||.|..|    ::|..|......:..:..:|....:..|.|.|.:
pombe  1200 HNIPFYGGFA---WLMLMIFTLYYT----TLGIGIATISPSIGTASIISGTAFVFIQYFNGMI-- 1255

  Fly   920 RIPEGL--SWIRYTSMIHYAYQNMQILEFREGAAIG------------------------CG--- 955
            ::|..:  .|....::..|.|       |.||...|                        ||
pombe  1256 QLPGVIVGFWKWMDALSPYKY-------FLEGMIGGVLHDAPITCEKFEIHYVDPPPNYSCGEYF 1313

  Fly   956 -------------SPSSYEICKQQSTEFIPYE 974
                         :|.:|..|     ::.||:
pombe  1314 SSFLNSSGHGIVYNPEAYSSC-----QYCPYK 1340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	159/687 (23%)
pdr1	NP_593995.1	3a01205	40..1382	CDD:273362	183/812 (23%)