Protein Alignment E23 and Abca5

DIOPT Version :9

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_671752.2
• Gene: Abca5 / 217265
• MGIID: 2386607
• Length: 1642
• Species: Mus musculus
• Alignment Length: 829
• Identity: 154/829 - (18%)
• Similarity: 296/829 - (35%)
• Gaps: 257/829 - (31%)

  Fly   348 QHSLQLTFQNLNVLHNERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDSG--SVF 410
            |.|.:...:|:..|.|       :|..:...::.|::|.||:||:||::.|.|......|  |::
Mouse   484 QKSYRKKTENVEALRN-------LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIY 541

  Fly   411 LNREPLTKKW---RRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALE 472
            .:|.....:.   |:.||...|.:|.|..||:.|.:   ::|...:.:|....:::|..:|..|:
Mouse   542 GHRVSEIDEMFEARKMIGICPQSDINFDVLTVEENL---SILASIKGIPANNIIQEVQKVLLDLD 603

  Fly   473 LGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLD---SHSAISLMKVLK-- 532
            :   |..|  |...:.||||:|::.::...:|.||.::||||||:|:|   .|...:|:|..|
Mouse   604 M---QAIK--DNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKAN 663

  Fly   533 ----------------------------------------------------RYAQLEQKTIVIS 545
                                                                ||...|..:.::.
Mouse   664 RVTVFSTHFMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVR 728

  Fly   546 VHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHF------EDIGVTIKPHYNPADFVLEQLKS 604
            .|.|::.:....|:.|:.    :..|.|:......|      .::||.   .|..:...||
Mouse   729 QHIPAAALLQQNDQQLVY----SLPFKDMDKFSGLFSALDIHSNLGVI---SYGVSMTTLE---- 782

  Fly   605 HPDIREKLFIAAKESHGNY-------------------LNRNCITSSHHNQVSVSG-AKGKKQAD 649
              |:..||.:.|:....:|                   :.::.:..|.....|||. :..|:|..
Mouse   783 --DVFLKLEVEAEIDQADYSVFTQQPREEETDSKSFDEMEQSLLILSETKASSVSTMSLWKQQVS 845

  Fly   650 SILIDDIINNYYNQRSNRH------------------HHQYENL-------------------HH 677
            :|.....::.....:|.|.                  ||.::|.                   |.
Mouse   846 TIAKFHFLSLKRESKSVRAVLLLLLIFFAVQIFMFFLHHSFKNAVVPIKLVPDLYFLKPGDKPHK 910

  Fly   678 TSNGCRVEEDEEA---------AQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSY 733
            ......::...::         |...:..|..:.|::.|.|     .:||......|..|...|.
Mouse   911 YKTSLLLQNSTDSDINGLIEFFAHQNIMVAMFNDSDYVSAA-----PHSAALNVVRSEKDYVFSA 970

  Fly   734 PTSFHTQFCVLSSRNFREAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFFSQT 798
            ..:....:|:          |.|::.::.:....|.:......:..|    |:.::...:|..:.
Mouse   971 VFNSTMVYCL----------PVMMNIISNYYLYHLNVTEAIQTWSTP----FIQEITDIVFKIEL 1021

  Fly   799 YWMLFALFGAL-NSFPSEREVVSKERRSGAYRLSAYYLAKMCAELP-------LVITLPTVYLMI 855
            |:.. ||.|.: .:.|....:.:.|.    :::.||...|:...||       .|:.:| ::.::
Mouse  1022 YFQA-ALLGIIVTAMPPYFAMENAEN----HKIKAYTQLKLSGLLPSAYWVGQAVVDIP-LFFVV 1080

  Fly   856 SYPMLGCTSLKLF----------FLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLAT 910
            ...|||  ||..|          ||.::|.||..:.:..:..:|        .|.|...:  |.|
Mouse  1081 LILMLG--SLFAFHHGLYFYPAKFLAVVFCLIAYVPSVILFTYI--------ASFTFKKI--LNT 1133

  Fly   911 QLFGGYLSS-------RIPEGLSWIRY--TSMIHYAYQNMQILEFREGAAIGCGSPSSYEICKQQ 966
            :.|..::.|       .|.|...:::|  |::.||.:    .:.......:||
Mouse  1134 KEFWSFIYSVTALACVAITETTFFLQYAVTAVFHYTF----CIAIPIYPLLGC------------ 1182

  Fly   967 STEFI--PYEEILKAQNSTSPLWLNTLILMMFFLVFRCLGYAVLRFLRC 1013
            ...||  .::.:.|.:|:.:| |...|:.:            ::.:|:|
Mouse  1183 LISFIKGSWKNMPKNENTYNP-WDRLLVAV------------IMPYLQC 1218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	ABCG_EPDR	350..572	CDD:213180	62/283 (22%)
		3a01204	363..1009	CDD:273361	148/808 (18%)
		ABC2_membrane	744..943	CDD:279410	43/225 (19%)
Abca5	NP_671752.2	rim_protein	<84..1618	CDD:130324	154/829 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000