Protein Alignment E23 and wht-6

DIOPT Version :9

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_498425.2
• Gene: wht-6 / 188911
• WormBaseID: WBGene00007060
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 693
• Identity: 181/693 - (26%)
• Similarity: 304/693 - (43%)
• Gaps: 154/693 - (22%)

  Fly   351 LQLTFQNLNV--LHNERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLD---CLSGQRHIDSGSVF 410
            :.|.:.|:.|  :..:|.:|.:|||:....|:||:||.||:||||||:   |.:.:.....|::.
 Worm    32 VSLHWNNITVTTIKEKRLLLKNVSGYAKSGELLALMGASGAGKTTLLNMLMCRNLKGLSTEGTIT 96

  Fly   411 LNREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQ--VDHILEALEL 473
            :|...:..|.....|:..|||:|...||::|.::..|.||:..|    :|:|:  |..:|..|:|
 Worm    97 VNGNEMAHKISSISGFAQQEELFVGTLTVKEYLMIQAKLRINGS----KKLREDRVTDVLHQLKL 157

  Fly   474 GCCQQTKFGDY-LNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQL 537
            ..|:.:|.|.. ..:|:||||.:|...|||:|:||.|:..||||:||||..|.|::::||..|:
 Worm   158 WKCRDSKIGVIGEKKGISGGEARRLTFACEMLSNPSLLFADEPTTGLDSFMAESVIQILKGIAK- 221

  Fly   538 EQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQL 602
            ..:||:.::||||||::.||.:::.|..|.||:.|..|.....||..|..:...|||:::::.:|
 Worm   222 TGRTIICTIHQPSSQLYQMFHRVIYLANGSTAFQGTPQESISFFEKCGHRVPDEYNPSEWIIYKL 286

  Fly   603 KSHPDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNR 667
            ...|.                                    .:||:             |.|..:
 Worm   287 AVQPG------------------------------------QEKQS-------------NDRIQK 302

  Fly   668 HHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLS 732
            ...|||:..|..   ||.|........:                          |
 Worm   303 IVEQYEDSDHQK---RVMEQLSDVSEKI--------------------------P---------- 328

  Fly   733 YPTSFH-----TQFCVLSSR---NFREAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDL 789
             |...|     ||...||:|   :...|....|:|:  .|.|...|..|.::.:.|.....:|::
 Worm   329 -PPEMHRANVFTQIFALSTRCGIDVWRAPQLTLAKV--IQKILFGLFIGLLYLRTPYDARGIHNI 390

  Fly   790 QGWMFF-------SQTYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVIT 847
            .|.:||       |..|.::|.|   .|.||    :|::|...|.|.|..||.|:..:.:||..|
 Worm   391 NGALFFLAGEYIYSTAYAIMFFL---NNEFP----LVAREYHDGLYNLWTYYFARCISLIPLFST 448

  Fly   848 LPTVYLMISYPMLGCTSLKLFFLMLIFLLINTIVAQSV--GFFIGACCMDMNVSIT--LSALYTL 908
            ...:.|.|.|.::|   |....:.:|...|.|::|...  .|.|...|:.....:|  :::...:
 Worm   449 DGLILLFIVYWLIG---LNTSVMQVIVASIITVLASQAASAFGIAMSCIFPTAQMTAVMASPPLV 510

  Fly   909 ATQLFGGYL--SSRIPEGLSWIRYTSMIHYAYQNM------QILEFREGAAIGCGSPSSYEICKQ 965
            ..:||||..  ::..|..:.|:::.||..:|::.:      :|.:|...|.....:.::.::
 Worm   511 LFRLFGGLYGNTNTFPAAIRWLQWISMYRFAFEGLVVNQWSEIDDFHSNAKNNWTNSTTNDV--- 572

  Fly   966 QSTEFIPYEEILKAQNSTSPLWLNTLILMMFFLVFRCLGYAVL 1008
              .::..:.|      |..||.:..|||:.  |.|..:|:..|
 Worm   573 --LDYFAFSE------SAIPLDIIGLILIS--LAFYLIGFIAL 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	ABCG_EPDR	350..572	CDD:213180	86/228 (38%)
		3a01204	363..1009	CDD:273361	178/679 (26%)
		ABC2_membrane	744..943	CDD:279410	55/220 (25%)
wht-6	NP_498425.2	P-loop_NTPase	<3..>81	CDD:393306	21/48 (44%)
		3a01204	50..613	CDD:273361	177/675 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720