Protein Alignment E23 and wht-2

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_502164.1
• Gene: wht-2 / 178069
• WormBaseID: WBGene00007513
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 680
• Identity: 188/680 - (27%)
• Similarity: 319/680 - (46%)
• Gaps: 122/680 - (17%)

  Fly   353 LTFQNLNVLHNE---RQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQ--RHID-SGSVFL 411
            ||:.|::: |.|   :|||.:|||...|.::||:||.||:||||||:.|..:  |.:: ||||.:
 Worm    34 LTWHNISI-HAEKSGKQILENVSGIAKPGQLLALMGASGAGKTTLLNMLLSRNLRGLETSGSVKV 97

  Fly   412 NREPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCC 476
            |...|.:......||..|:|:|...||::|.:...|.||:  :....::.|:|.:::..|.|..|
 Worm    98 NGHELGRGITAISGYAQQDELFVGTLTVKEYLDIQAKLRV--NGDSEKRRRRVGNVMSQLGLYKC 160

  Fly   477 QQTKFGDY-LNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQK 540
            |.|:.|.. ..:|:||||.:|...|||||:||.::..||||:||||..|.|:::||...|: ..:
 Worm   161 QNTRIGTIGGQKGISGGEMRRLTFACELLSNPSILFCDEPTTGLDSFMAESVVQVLSNLAK-SGR 224

  Fly   541 TIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSH 605
            |::.::||||||::.|||:::.:..|:||:.|..::..:.|||.|.....::||||.::..|...
 Worm   225 TVICTIHQPSSQLYLMFDRVMFMAGGKTAFLGSPRDAIQFFEDAGFACPRNFNPADLIIHTLAVM 289

  Fly   606 PDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHH 670
            |:..:|.....:..:..:.|     ||:...:..    |.:::|.           .||.:..|
 Worm   290 PNEEDKCRQRIEVIYTKFQN-----SSYGRTLKF----GVEKSDE-----------GQRPSERH- 333

  Fly   671 QYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPT 735
              :....|..|..:|                                      .||.|.|
 Worm   334 --KTGILTQIGALLE--------------------------------------RSAIDTW----- 353

  Fly   736 SFHTQFCVLSSRNFREAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLHDLQGWMFFSQTYW 800
                       ||....:.:::.|     :| :.|..|.::.|.|.|...:.:|.|.:|:.....
 Worm   354 -----------RNPSLTRAKVIQK-----SI-MGLFIGLLYLQSPLTSIGISNLNGALFYLVCEL 401

  Fly   801 MLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLGCTS- 864
            ....:||.||..|::..:||:|...|.|.:.:||:|:..:.|||......:.|::||.|:|.:|
 Worm   402 TYSTIFGILNFLPADFPLVSREYHDGLYSVFSYYVARCLSYLPLFTADGLIMLLVSYWMVGFSSS 466

  Fly   865 -LKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLAT--QLFGGYLSS--RIPEG 924
             .::.:..||..||.. .:.:.|..|.  |:..::.|.:|....:.|  .|.||..::  .:|..
 Worm   467 ITQVLYACLIAFLIEQ-SSSACGIMIS--CISPSLPIAMSTAGPMLTLLSLTGGLYANVGALPSY 528

  Fly   925 LSWIRYTSMIHYAYQNMQILEFREGAAIGCGSPSSYEICKQQSTEFIPYEE---ILKAQNSTSPL 986
            :|||:|.|...|.::...|              :.:....:|:|.....|:   :|...:..:.:
 Worm   529 ISWIQYLSWFRYGFEAFAI--------------NQWSSVNEQNTTIWTDEKRDSVLSQLSFRAEM 579

  Fly   987 WLNTLILM-MFFLVFRCLGYAVLRFLRCPK 1015
            :...|.:| .|.|:|..:|||.|. ||..|
 Worm   580 FYPDLFIMSAFILIFYTIGYAGLA-LRVSK 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	180/662 (27%)
wht-2	NP_502164.1	3a01204	44..610	CDD:273361	184/669 (28%)