Protein Alignment E23 and abch-1

DIOPT Version :9

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: NP_495320.1
• Gene: abch-1 / 174078
• WormBaseID: WBGene00016973
• Length: 595
• Species: Caenorhabditis elegans
• Alignment Length: 678
• Identity: 156/678 - (23%)
• Similarity: 245/678 - (36%)
• Gaps: 168/678 - (24%)

  Fly   366 QILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDSGSV-FLNREPLTK----KWRRRIG 425
            |||.::|...:..|:.||:|.:.|||||||:.|:.....|.|.: .|::..||:    |:...|.
 Worm    35 QILKNISFTATSGEIHAIVGVADSGKTTLLEALTSGAGGDIGGIAMLDKFMLTRRRFNKFCSHIN 99

  Fly   426 YVLQEEIFFP-QLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALE-----LGCCQQTKFGDY 484
            |..|    :| .|::|..:.|.|.|.|..:....|    :||.:..|.     :|.... |..|
 Worm   100 YRNQ----YPSSLSVRSLLYYHARLCLSSTHTSLE----IDHRISELSAMFDVIGYAHD-KLED- 154

  Fly   485 LNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQP 549
                ||...::|.....|||.:|:|.::|:||:.|...||..|:..|..||....:.|:|::...
 Worm   155 ----LSFSARRRVMTVMELLKDPILTIIDDPTAYLSPLSAYQLIYALHFYAAKFNRIIIITLRNV 215

  Fly   550 SSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSHPDIREKLFI 614
            .|.:.|:......|..|..||.|.::.:..||:..|....|:.|||.:.|..|....:..:|
 Worm   216 RSDLSHLLGSATCLFYGEVAYSGQMRLLPNHFKKAGFECPPNENPAAYYLSLLTIDKESMQK--- 277

  Fly   615 AAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTS 679
                                                                             
 Worm   278 ----------------------------------------------------------------- 277

  Fly   680 NGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVL 744
                |.|.:|.|..||....|:.:      |||. |.|:.:|.|...|....:  .|..|...:|
 Worm   278 ----VMETQEKATKLVAFRTDNDT------SSDI-SGSSATGTGVLLDSGRKN--PSISTVAAIL 329

  Fly   745 SSRNFREAKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFLH-----DLQGWMFFSQTYWMLFA 804
                ||    |:||.:....:..|   ||.|.|  |.|...|.     .|...:||.:....|:.
 Worm   330 ----FR----RVLSLIGSTPSNSL---AGLIAF--PVTAAVLSFLRPTSLPSSLFFWKLLTFLYL 381

  Fly   805 LFGALNSFP--------SEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLG 861
            |...:..||        |.||.....:.:.....|.::|...|.:..|.:.: .::...|..|..
 Worm   382 LLQTIVIFPNYSKTSLLSFRECNLYCQTTSLTIFSIFFLVYSCIQSSLFVGI-VLWSFKSEAMFQ 445

  Fly   862 CTSLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNV----SITLSALYTLATQLFGGYLSSRIP 922
             .||.||.|.:....|.||.|:    ::..|   .|:    :|.:.|.:.....:.|...||.|.
 Worm   446 -ISLNLFLLSIFSFSIFTICAR----YLKNC---SNIVILQTIIILAFFVSGNGVTGTTTSSSIQ 502

  Fly   923 EGLSWIRYTSMIH-YAYQNMQILEFREGAAIG--CGSPSSYEICKQQSTEFIPYEEILKAQNSTS 984
                  .|..:|: :.|.|..:.:....:...  |..||  .:||..          :...:...
 Worm   503 ------YYIGVINPFNYSNFLLSKLLSSSIDNEECTFPS--YMCKLS----------MNLHSDLY 549

  Fly   985 PLWLNTLILMMFFLVFRCLG--YAVLRF 1010
            |.|.....:...|.:..||.  :.|:.|
 Worm   550 PPWYAPNDVFTNFAILFCLSLTFLVISF 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	ABCG_EPDR	350..572	CDD:213180	65/216 (30%)
		3a01204	363..1009	CDD:273361	155/675 (23%)
		ABC2_membrane	744..943	CDD:279410	51/216 (24%)
abch-1	NP_495320.1	P-loop_NTPase	18..238	CDD:393306	65/216 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810