Protein Alignment E23 and st

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: XP_310585.5
• Gene: st / 1271735
• VectorBaseID: AGAMI1_007970
• Length: 689
• Species: Anopheles gambiae
• Alignment Length: 659
• Identity: 177/659 - (26%)
• Similarity: 305/659 - (46%)
• Gaps: 101/659 - (15%)

  Fly   365 RQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQR---HIDSGSVFLNREPLTKKWRRRIGY 426
            ::|:::|||.|:|..::|:||.||:||:||:..|:.:.   .:..|.:.:|.:|:.....|..|:
Mosquito   111 KRIINNVSGAVTPGTLIALMGSSGAGKSTLMSALAYRTPPGTVVQGDILVNGQPVGPYMYRLSGF 175

  Fly   427 VLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLN-RGLS 490
            |.|:::|...||:.|.:.:.|.|||...:......:.:..:||.:.|..|..|:.|:..: :.||
Mosquito   176 VHQDDLFVGSLTVHEHMYFMAKLRLDRRVGHRAIDQTIRDLLERVGLARCAGTRIGEAGDGKMLS 240

  Fly   491 GGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMFH 555
            ||||||...|.||||.|.|:..||||:||||:.|.:|:..|::.|: ....|:.::||||||:|.
Mosquito   241 GGEKKRLAFATELLTKPTLLFCDEPTTGLDSYGAQALVSTLQQLAR-RGTAIICTIHQPSSQLFS 304

  Fly   556 MFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPADFVLEQLKSHPDIREKLFIAAKESH 620
            |||:::||.:||.||.|........|...|....|.||||::::..|.:.|...:....||
Mosquito   305 MFDQVMLLAEGRVAYAGRPHEALAFFARHGHACPPSYNPAEYLIGALATAPGYEQASQRAA---- 365

  Fly   621 GNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINNYYNQRSNRHHHQYENLHHTSNGCRVE 685
                :|.|      :..:||.|.|::        |::.|.             .:|...:|....
Mosquito   366 ----HRLC------DLFAVSEAAGQR--------DVLINL-------------EVHMAESGDYRV 399

  Fly   686 EDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGPGHSADDDWLSYPTSFHTQFCVLSSRNFR 750
            .||  .|||                         :|..|     || :.|::.|...:|:
Mosquito   400 TDE--VQHL-------------------------AGRPH-----WL-HTTAWLTYRALLT----- 426

  Fly   751 EAKPRMLSKLNWFQTIGLALMAGAIWF-QLPRTEEFLHDLQGWMFF---SQTYWMLFALFGALNS 811
            ..:...:..|...|.|.:|||||..:. .:..|:..:...||.:|.   ..|:..::|:   |..
Mosquito   427 VVRDPTVQYLRLLQKIAIALMAGLCFTGAIEPTQLGVQATQGLLFILISENTFTPMYAV---LAV 488

  Fly   812 FPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTVYLMISYPMLGCTSLKLFFLM---LI 873
            ||....:..:|.::|.|..|.||:|.:.|.||.::..|.|:::|:|.:.........||:   ..
Mosquito   489 FPETFPLFMRETKNGLYHPSQYYVANVAAMLPGLVLEPLVFVLIAYWLAALRPTLHAFLVTAAAA 553

  Fly   874 FLLINTIVAQSVGFFIGACCMDMNVSITLSALYTLATQLFGG---YLSSRIPEGLSWIRYTSMIH 935
            .|::|  |:.:.|.|..|....:.:::.....:.....:..|   :|:: :|....|:.|.|.:.
Mosquito   554 TLVMN--VSTACGCFFSAAFNSLPLAMAYLVPFDYILMITSGVFIHLNT-MPAATRWLPYISWMM 615

  Fly   936 YAYQNMQILEFREGAAIGCGSPSSYEICKQQSTEFIPYEEILKAQNSTSP-LWLNTLILMMFFLV 999
            ||.:.|.|.::...:.|.|.:......|.:...|.:  |....::...:| ||    .:::.:..
Mosquito   616 YANEAMSIAQWEGVSNITCPAVDDKLPCLRTGGEVL--EHYSFSETHLAPNLW----AMVLLYFG 674

  Fly  1000 FRCLGYAVL 1008
            |..|||..|
Mosquito   675 FHLLGYLFL 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	177/659 (27%)
st	XP_310585.5	None