Protein Alignment E23 and LOC1271438

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: XP_310233.4
• Gene: LOC1271438 / 1271438
• VectorBaseID: AGAMI1_011474
• Length: 657
• Species: Anopheles gambiae
• Alignment Length: 760
• Identity: 185/760 - (24%)
• Similarity: 319/760 - (41%)
• Gaps: 160/760 - (21%)

  Fly   277 SQTTIPSTDNLTSSNGLANIGKSILVDAKSNSPASLSYH----FEKSAAANQ-QKQHHNINICNS 336
            :|||:|.  |...|.   |:.::::   ::|:..::|.|    |:...|... ..|..:::.|.|
Mosquito    26 NQTTVPL--NRKDSR---NMDQAVI---RNNTANAVSNHELRPFQNLPAREPVDIQFKDVSYCVS 82

  Fly   337 HHPHHHSQNQPQHSLQLTFQNLNVLHNERQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQ 401
                                 |.....:::||.:|:|.....:::|||||||:||:||||.|||.
Mosquito    83 ---------------------LGFRKGQKEILHNVNGKFPGSQLIAIMGPSGAGKSTLLDVLSGY 126

  Fly   402 RHID-SGSVFLN-REPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQV 464
            |... .|:|::| |......:||...|:.|::.....||:.|.:...|.|:|...:.|.||...|
Mosquito   127 RRTGVEGAVYVNGRIRNLNSFRRMTCYITQDDRLQTLLTVVENMRIAADLKLGPEVSRHEKESIV 191

  Fly   465 DHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMK 529
            :.||..|.|...|.|     :.:.||||::||.:||.||:.||.:|.|||||:||||.|...::.
Mosquito   192 EDILTVLGLYNHQFT-----ITKLLSGGQRKRLSIALELINNPTIMFLDEPTTGLDSSSCNQVVD 251

  Fly   530 VLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNP 594
            :||:.|: :.:||:.::||||:::|..||::.:|..|...|.|...::....:.:.:....::||
Mosquito   252 LLKQLAK-QGRTIICTIHQPSAKLFQEFDQVYVLSNGECMYQGCTNSLVPFLQSVDMPCPVYHNP 315

  Fly   595 ADFVLEQLKSHPDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILID----D 655
            ||:|:|                                     ...|..|:::...::::    :
Mosquito   316 ADYVIE-------------------------------------LACGEYGEERIQRMVMEMGNGE 343

  Fly   656 IINNYYNQRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGS 720
            ....:.::|......|....:....  .:|::|:..                 |:|..|
Mosquito   344 CTEWFTDKRKLLKPEQLRQKYPLKK--IIEQNEDLT-----------------ATSQVH------ 383

  Fly   721 GPGHSADDDWLSYPTSFHTQFCVLSSRNFREAK-PRMLSKLNWFQTIGLALMAGAIWFQLPRTEE 784
                               |..||..|...:|| ...|:.|.....|.:|.|.|.::........
Mosquito   384 -------------------QLQVLIKRGIIKAKRDATLTHLRIGVNIIIAAMLGFLFIDAGNEGS 429

  Fly   785 FLHDLQGWMFFSQTYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLP 849
            .:.|....:|....:.|:..:...:.:||:|..|:.||..:..|.|..|||:....:|||.:...
Mosquito   430 RVLDNYNLLFSILMHHMMATMMLTVLTFPTEMGVILKEHFNRWYTLKCYYLSVSIIDLPLSVFCC 494

  Fly   850 TVYLMISYPMLGCTSLKLFFLMLIFL--LINTIVAQSVGFFIGACCMDMNVSITLSALYTLATQL 912
            .::.:|.|.|.| ..::.|...:.|.  |:..::|||:|..|||....:|.:. |..:.|:...:
Mosquito   495 LIFTIIIYLMSG-QPMEWFRFGMFFTISLLIVLIAQSIGLTIGAWFNVVNGTF-LGPVLTIPMMM 557

  Fly   913 FGGY-LSSR-IPEGLSWIRYTSMIHY---AYQNMQILEFREGAAIGCGSPSSYEICKQQSTEFIP 972
            |.|: ::.| :|..|.|..:.|.:.|   .|.|....|.||  .:.|              |..|
Mosquito   558 FAGFGVTLRDLPSYLKWGSHISYLRYGLEGYVNAIYGENRE--TLDC--------------ELKP 606

  Fly   973 Y-------EEILKAQNSTSPLWLNTLILMMFFLVFRCLGYAVLRF 1010
            |       :.:.:........|.:...|....|:.|...|..||:
Mosquito   607 YCHYRYPAKFLSEISMEGDQFWKDVYALCATLLLVRVCCYFCLRW 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	167/666 (25%)
LOC1271438	XP_310233.4	3a01204	61..653	CDD:273361	175/717 (24%)