Protein Alignment E23 and abcg4

DIOPT Version :10

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: XP_004916110.1
• Gene: abcg4 / 101734071
• XenbaseID: XB-GENE-22063023
• Length: 639
• Species: Xenopus tropicalis
• Alignment Length: 684
• Identity: 189/684 - (27%)
• Similarity: 319/684 - (46%)
• Gaps: 120/684 - (17%)

  Fly   347 PQHS-LQLTFQNLNVLHNE---------RQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQ 401
            |:.| :.:.|::|:....|         :.:|..:||.....|::.||||||:||:||::.|:|.
 Frog    50 PKRSAVDIEFKDLSYSVREGPCWRKRGYKTLLKCLSGMFCSRELIGIMGPSGAGKSTLMNILAGY 114

  Fly   402 RHID-SGSVFLN-REPLTKKWRRRIGYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQV 464
            |... :|.:.:| ::...:.:|:...|::|:::..|.||::|.::.:..|:|.|.|...:|:  |
 Frog   115 RESGMTGQILVNGKQRELRTFRKMSCYIMQDDMLLPHLTVKEAMMVSTNLKLNEKMEVKKKL--V 177

  Fly   465 DHILEALELGCCQQTKFGDYLNRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMK 529
            :.||.||.|..|..|:     ...||||::||..||.||:.||.:|..|||||||||.|...::.
 Frog   178 NEILTALGLLDCSGTR-----TLFLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVS 237

  Fly   530 VLKRYAQLEQKTIVISVHQPSSQMFHMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNP 594
            :|...|| ..:||:.::||||:::|.||:||.:|.||:..|.|.|.::..:.:.:|:....::||
 Frog   238 LLNSLAQ-GGRTIICTIHQPSAKLFEMFNKLYILSQGQCIYRGSVTHLIPYLKGLGLHCPTYHNP 301

  Fly   595 ADFVLEQLK-SHPDIREKLFIAAKESHGNYLNRNC-ITSSHHNQVSVSGAKGKKQADSILIDDII 657
            |||::|... .:.|:...||.|.::.       .| ||.....|..:
 Frog   302 ADFIIELASGEYGDLNPLLFRAVEDG-------LCPITRDKSQQTKL------------------ 341

  Fly   658 NNYYNQRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGP 722
                                         |:|   |   |..|...:..|      |:::
 Frog   342 -----------------------------DQE---H---CPNDVSVHVES------HTFA----- 360

  Fly   723 GHSADDDWLSYPTSFHTQFCVLSSRNFRE-AKPRMLSKLNWFQTIGLALMAGAIWFQLPRTEEFL 786
                        ||...|||:|..|.|.. .:..:|:.|.:...:.:.::.|.::..:......:
 Frog   361 ------------TSSLNQFCILFKRTFLSILRDTVLTHLRFMSHLCIGVLIGLLYLHIGDDASKV 413

  Fly   787 HDLQGWMFFSQTYWMLFALFGALNSFPSEREVVSKERRSGAYRLSAYYLAKMCAELPLVITLPTV 851
            .:..|::|||..:.|..||...:.:||.|..|..:|..:..|.|.||||||..|::|..|..|..
 Frog   414 FNNTGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIVCPVA 478

  Fly   852 YLMISYPMLGCTSLKLFFLMLIFLLINT-IVAQSVGFFIGACCMDMNVSITLSALYTLATQLFGG 915
            |..|.|.|.........||:...|..:| :||||:|..||.....:.|:..:..:..:...||.|
 Frog   479 YCSIVYWMTSQPPEVSRFLLFSALATSTALVAQSLGLLIGVASNSLQVATFVGPVTAIPVLLFSG 543

  Fly   916 YLSS--RIPEGLSWIRYTSMIHYAYQNMQILEF-REGAAIGCGS-PSSYEICKQQSTEFIPYEEI 976
            :..|  .||..|.|..|.|.:.|.::.:.:..: .:.|.:.|.. |.:::: .||..:.:..|:
 Frog   544 FFVSFKTIPTYLQWCSYISYVRYGFEGVILAIYGMDRAPLQCRELPCTFQL-PQQVLQELDVED- 606

  Fly   977 LKAQNSTSPLWLNTLILMMFFLVFRCLGYAVLRF 1010
                   :.|:::.|:|..|||..|.|.|.|||:
 Frog   607 -------AKLYVDFLVLGGFFLGLRLLAYLVLRY 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	3a01204	363..1009	CDD:273361	183/664 (28%)
abcg4	XP_004916110.1	3a01204	40..639	CDD:273361	189/684 (28%)