Protein Alignment E23 and abca10

DIOPT Version :9

• Sequence 1: NP_524648.3
• Gene: E23 / 43895
• FlyBaseID: FBgn0020445
• Length: 1017
• Species: Drosophila melanogaster
• Sequence 2: XP_031750511.1
• Gene: abca10 / 100485734
• XenbaseID: XB-GENE-6464279
• Length: 1610
• Species: Xenopus tropicalis
• Alignment Length: 747
• Identity: 148/747 - (19%)
• Similarity: 279/747 - (37%)
• Gaps: 199/747 - (26%)

  Fly   300 ILVDAKSNSPASLSYHFEKSAAANQQKQHHNINICNSHHPHHHSQNQPQHSLQLTFQNLNVLHNE 364
            ::.....:..:||.:..||..|....|:...|                 |.::.|:.:.:   ..
 Frog   448 LMAQTDDSGESSLGHFVEKVPADLHGKEAIRI-----------------HGVKKTYYDKD---KN 492

  Fly   365 RQILSDVSGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDSGSVFLNREPLTK-----KWRRRI 424
            .:.|.|:...:...::.|::|.||:||||||:.|||......||..:....|:.     :.::|:
 Frog   493 TEALRDLDLNIYEGQITALLGHSGAGKTTLLNILSGMCPTSGGSATVCNYKLSNMRHLGEIKKRV 557

  Fly   425 GYVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYLNRGL 489
            |:..|.:|.|..||::|.:...|:::   .:|..|...:|..:|..|::...:..:...     |
 Frog   558 GFCPQGDIKFDPLTVKENLTVFAMIK---GIPSKEVAHKVQTVLSDLQMNDIENIEASK-----L 614

  Fly   490 SGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVISVHQPSSQMF 554
            |||:|::......:|.:|.::||||||:|||..|..::..:||. ::.::.|::.:.....:.:
 Frog   615 SGGQKRKLTFGIAILGDPQVLLLDEPTAGLDPCSRHNIWTILKE-SKADRVTLLSTQFMDEADI- 677

  Fly   555 HMFDKLLLLHQGRTAYFGDVQNIYRHFEDIGVTIKPHYNPA---DFVLEQLKSH----------- 605
             :.|:.:::.:|:....|....:.|.: .:|..::...:|:   :.:...:|.|
 Frog   678 -LADRKVVISKGKLKCVGTSLFLKRKW-GVGYHLRMQVSPSCDVELMTSIIKQHIPSTKLTTQNE 740

  Fly   606 -----------PDIREKLFIAAKESHGNYLNRNCITSSHHNQVSVSGAKGKKQADSILIDDIINN 659
                       .|:...||:......||.:....::.:..:.|.:. .:|:.:.:|       .:
 Frog   741 EELTYTLPFENMDVFPDLFLHLDGQVGNSIVNYGVSMTTLDDVFLK-LEGEGEIES-------GD 797

  Fly   660 Y--YNQRSNRHHHQYENLHHTSNGCRVEEDEEAAQHLVWCAADSQSNFSSCASSDCHSYSAGSGP 722
            |  :|..|                 |..||.|              :||:.........|.....
 Frog   798 YDVFNPES-----------------RTNEDRE--------------DFSTEMEESLLQMSDSGNV 831

  Fly   723 GHSADDDWLSYPTSFHTQFCVLSSRNFREAKPRMLSKLNWFQTIGLAL----------------- 770
            ..|..:.|...         ||:....|..|.|..:|.  |::|.|.|
 Frog   832 TLSGWELWRQQ---------VLAVARIRLLKLRHDTKS--FRSILLLLVVITLPPIIIIITSNIV 885

  Fly   771 -------MAGAIWFQLPRT--EEFLHDLQGWMFFSQTYWMLFALFGALNSFPSEREVVSKE---- 822
                   :...::||.||.  .::..||   :..:.|...:....||:.....|.:||:.|
 Frog   886 NTFDAWELTPHLYFQSPRNRLNKYYTDL---LICNNTGSSIEDFVGAVKEQNIEVQVVNGEYDTE 947

  Fly   823 --RRSGAYRLSAY---YLAKMCAELPLVITLPTVYLMISYPML-------------------GCT 863
              :..||..:|..   |...:.|......:||.:..:||..:|                   |..
 Frog   948 TVKYRGAIEVSQMEKGYNFTIVANPKAFNSLPVLLNIISNALLKILKVSGHFRVWNHPITTDGTD 1012

  Fly   864 SLKLFFLMLIFLLINTIVAQSVGFFIGACCMDMNVSIT------------LSALYTLATQLFGGY 916
            .:.|.::.|||.:|          |..|.|..:.:|.|            :|.|:..| ..||..
 Frog  1013 IIFLPYMSLIFFII----------FASAFCPHIAMSSTEDNRINARNQLRISGLFPSA-YWFGQA 1066

  Fly   917 LSSRIPEGLSWIRYTSM--IHYAYQNMQILEF 946
            |...|   |.||....|  |::|:.:..:|:|
 Frog  1067 LVDVI---LYWILLFLMVAIYFAFNSYILLDF 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E23	NP_524648.3	ABCG_EPDR	350..572	CDD:213180	55/226 (24%)
		3a01204	363..1009	CDD:273361	139/684 (20%)
		ABC2_membrane	744..943	CDD:279410	56/266 (21%)
abca10	XP_031750511.1	rim_protein	<107..1597	CDD:130324	148/747 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000