| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001077005.1 | Gene: | FGD3 / 89846 | HGNCID: | 16027 | Length: | 725 | Species: | Homo sapiens |
| Alignment Length: | 629 | Identity: | 132/629 - (20%) |
|---|---|---|---|
| Similarity: | 215/629 - (34%) | Gaps: | 191/629 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1334 PPPPTDPPVMSEEMITGLIVP--APGWNGTSKDLYSPEAESSPATSFVDPAAMAAQLAVGGVGGV 1396
Fly 1397 VVGGLGVAKPTSRTSSFEIENLLKTAEQETRKSSPTGSVT-----------SSVSTTAL------ 1444
Fly 1445 ---------------------------TPSRQLTDA--------EKLRKVVMELVDTERTYVKHL 1474
Fly 1475 NNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFL-----QNLEESLDLEPDFNKFEHCG 1534
Fly 1535 QFRNVLFAIGSAFLYYVNHFKLYSSFCASHSKAQKVLHP--------NEGNHALQEFLAARNPKQ 1591
Fly 1592 Q--HSSTLESYLIKPIQRILKYPLLLQQ-MRNLTDTRADEHVHLCEALKGMEKV---AEHIN--- 1647
Fly 1648 ----EMQRIHEEYGAIFDHLFRQHQKSCKQPIDLSPGDLLYYGGVEWLNISDFLGKIKKGLELHA 1708
Fly 1709 MCFVFKSAVVFLCKERLRQKKKLMGVSSKNATNEVEIIRYQVLIPVTEVQVRASSAKDMDSHFLW 1773
Fly 1774 ELIHLRS-QLQRRSEKVYVLSNSTADFRNAFLKTIRQIIRESVRNMSIPMKNFGGSSGSVSGHSS 1837
Fly 1838 QGMGSMGYPGNSQTLERPKQQITIVHGSHTLG--KPKKKSGSQR 1879 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | |||
| RhoGEF | 1456..1647 | CDD:238091 | 47/209 (22%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 34/173 (20%) | ||
| PH | 1693..1812 | CDD:278594 | 24/119 (20%) | ||
| FGD3 | NP_001077005.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..151 | 33/168 (20%) | |
| RhoGEF | 160..339 | CDD:238091 | 46/207 (22%) | ||
| PH1_FGD3 | 371..478 | CDD:275422 | 30/140 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 487..532 | 10/44 (23%) | |||
| FYVE_FGD3 | 531..584 | CDD:277279 | 132/629 (21%) | ||
| PH2_FGD1-4 | 598..702 | CDD:270056 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 703..725 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||