| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001397626.1 | Gene: | PLEKHN1 / 84069 | HGNCID: | 25284 | Length: | 663 | Species: | Homo sapiens |
| Alignment Length: | 366 | Identity: | 83/366 - (22%) |
|---|---|---|---|
| Similarity: | 109/366 - (29%) | Gaps: | 136/366 - (37%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 402 PMPSTESPVTSPEMGRRRYNYYNANAAQT------LGHPPHMHQHGMAMGM--GGGGGGGHHIMN 458
Fly 459 NNTMGRAS----------SQSSRFSGSRSSHEIGRGYPPRNLYLEL-ERERSCIEGSPPSDNVMF 512
Fly 513 DNQCYATTPSSSNGNSDQDQSYGQQQSSGQHPQQQQGPPQRSSRHQHHHQQAPNVTPTPGSPTSR 577
Fly 578 LLLEYEMHLRNTLAKGMDAESYSLHTFEALLSQSMENL----------EFAESLPGSNQRS---- 628
Fly 629 ---PYPLRRPNAKSSTL------------PLPPHRPLSTIRDKERDRD-----RDGYYSDRNELI 673
Fly 674 RERERERDRGY--LSDHNSSFSNSRCASCIGESAR---AQW 709 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| Tiam_CC_Ex | 999..1096 | CDD:408184 | |||
| RBD | 1141..1207 | CDD:128731 | |||
| PDZ | 1220..1299 | CDD:214570 | |||
| RhoGEF | 1456..1647 | CDD:238091 | |||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | |||
| PHA03307 | 2227..>2510 | CDD:223039 | |||
| PLEKHN1 | NP_001397626.1 | PH-like | 96..229 | CDD:473070 | |
| PH_PLEKHN1 | 268..388 | CDD:270132 | 5/12 (42%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||