| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_016870597.1 | Gene: | VAV2 / 7410 | HGNCID: | 12658 | Length: | 896 | Species: | Homo sapiens |
| Alignment Length: | 593 | Identity: | 124/593 - (20%) |
|---|---|---|---|
| Similarity: | 225/593 - (37%) | Gaps: | 161/593 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1450 LTDAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFL 1514
Fly 1515 QNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHFKLYSSFCASHSKAQKVLHPNEGNHA 1579
Fly 1580 LQEFLAARNPKQQH-----------SSTLESYLIKPIQRILKYPLLLQQMRNLTDTRADEHVHLC 1633
Fly 1634 EALKGMEKVAEHINEMQRIHE------EYGAIFDHLFRQHQKSCKQPIDLSPGDLLYYGGVEWLN 1692
Fly 1693 ISDFLGKIKKGLELHAMCFVFKSAVVFLCKER--LRQKKKLMGVSSKNATNEVEIIRYQVLIPVT 1755
Fly 1756 EVQVRASSAKDMDSH------FLWE----------LIHLRSQLQRRSEKVYVLSNSTADFRNAFL 1804
Fly 1805 KTIRQIIRESVRNMSIPMKNFGGSSGSVSGHSSQGMGSMGYPGNSQTLERPKQQITIVHGSHTLG 1869
Fly 1870 KPKKKSGSQRH-------------SAGNIDYDNLSGSQEADDLPPSVGVVHYASGHTHGQQMQPA 1921
Fly 1922 GFRGRSKTV-----GDVTEITCSSPEPHQQQQQQQQQQQQLMQQGHAHAHP----HPHPHPREPP 1977
Fly 1978 --PPPIRQ 1983 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | |||
| RhoGEF | 1456..1647 | CDD:238091 | 45/201 (22%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 33/196 (17%) | ||
| PH | 1693..1812 | CDD:278594 | 24/136 (18%) | ||
| VAV2 | XP_016870597.1 | CH_VAV2 | 2..120 | CDD:409112 | |
| RhoGEF | 202..375 | CDD:214619 | 46/199 (23%) | ||
| PH_Vav | 389..534 | CDD:269930 | 32/188 (17%) | ||
| C1_VAV2 | 537..594 | CDD:410418 | 10/63 (16%) | ||
| SH3_VAV2_1 | 608..667 | CDD:212913 | 16/76 (21%) | ||
| SH2_Vav2 | 685..787 | CDD:198269 | |||
| SH3_VAV2_2 | 837..894 | CDD:212910 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1291 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||