Protein Alignment sif and Arhgef9

DIOPT Version :9

• Sequence 1: NP_001261446.1
• Gene: sif / 43892
• FlyBaseID: FBgn0085447
• Length: 2734
• Species: Drosophila melanogaster
• Sequence 2: XP_038955963.1
• Gene: Arhgef9 / 66013
• RGDID: 620719
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 409
• Identity: 103/409 - (25%)
• Similarity: 168/409 - (41%)
• Gaps: 101/409 - (24%)

  Fly  1437 SSVSTTALTPS-------RQLTDAEKLR-KVVMELVDTERTYVKHLNNLLEHYLEP-MKRETFLS 1492
            |.|....|.|:       |.|.:.:::| .|:.|::.|||.|:|||.::.|.||:. .||....|
  Rat    84 SDVQNGHLDPNSDCLCLGRPLQNRDQMRANVINEIMSTERHYIKHLKDICEGYLKQCRKRRDMFS 148

  Fly  1493 NAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHFKLY 1557
            :.::..:||||.:|..||..|:::||:..:     |...|       |..||..||.:.:.|.:|
  Rat   149 DEQLKVIFGNIEDIYRFQMGFVRDLEKQYN-----NDDPH-------LSEIGPCFLEHQDGFWIY 201

  Fly  1558 SSFCASHSKA----QKVLHPNEGNHALQEFLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQM 1618
            |.:|.:|..|    .|::..:...|.   |.|.|..:|.....::.:|:.|:|:|.||||.|.::
  Rat   202 SEYCNNHLDACMELSKLMKDSRYQHF---FEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAEL 263

  Fly  1619 RNLTDTRADEHVHLCEALKGMEKVAEHINEMQR-------------------------------- 1651
            ...|.....::.::..||..|..|.:.|||.:|
  Rat   264 LKYTAQDHSDYRYVAAALAVMRNVTQQINERKRRLENIDKIAQWQASVLDWEGDDILDRSSELIY 328

  Fly  1652 ------IHEEYGA-------IFDHLFRQHQKSCKQPIDLSPGDLLYYGG------VEWLNI---- 1693
                  |::.||.       :|||    ....||:  ||...|:|||.|      .|.::|
  Rat   329 TGEMAWIYQPYGRNQQRVFFLFDH----QMVLCKK--DLIRRDILYYKGRIDMDKYEVIDIEDGR 387

  Fly  1694 -SDFLGKIKKGLELH-------AMCFVFKSAVVFLCKERLRQKKKLMGVSSKNATNEVEIIRYQV 1750
             .||...:|...:||       .:.|..|...........|:::|::....|......|..:.|.
  Rat   388 DDDFNVSMKNAFKLHNKETEEVHLFFAKKLEEKIRWLRAFREERKMVQEDEKIGFEISENQKRQA 452

  Fly  1751 LIPVTEVQVRASSAKDMDS 1769
            .:.|.    :||..|.::|
  Rat   453 AMTVR----KASKQKGVNS 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sif	NP_001261446.1	WH1	35..144	CDD:214674
		PH1_Tiam1_2	860..985	CDD:269937
		PH	873..974	CDD:278594
		TIAM1_RBD	1141..1219	CDD:176413
		PDZ_signaling	1221..1308	CDD:238492
		RhoGEF	1456..1647	CDD:238091	59/196 (30%)
		PH2_Tiam1_2	1650..1823	CDD:269957	35/183 (19%)
		PH	1693..1812	CDD:278594	18/89 (20%)
Arhgef9	XP_038955963.1	SH3_ARHGEF9	14..75	CDD:212908
		RhoGEF	114..293	CDD:214619	59/193 (31%)
		PH_Collybistin_ASEF	298..437	CDD:269931	26/144 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910