| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_062645.2 | Gene: | Net1 / 56349 | MGIID: | 1927138 | Length: | 595 | Species: | Mus musculus |
| Alignment Length: | 698 | Identity: | 127/698 - (18%) |
|---|---|---|---|
| Similarity: | 239/698 - (34%) | Gaps: | 220/698 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1342 VMSEEMITGL-----------------------IVPAPGWNGTSK----------------DLYS 1367
Fly 1368 PEAESSPATSFVDPAAMAAQLAVGGVGGVVVGGLGVAKPTSRTSSFEIENLLKTAEQETRKS--- 1429
Fly 1430 SPTGSVTSSVSTTALTPSRQ-----------------LTDAE-KLRKVVMELVDTERTYVKHLNN 1476
Fly 1477 LLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLF 1541
Fly 1542 AIGSAFLYYVNHFKLYSSFCASHSKAQKVLHPNEGNHALQEFLAARNPKQQHSSTLE--SYLIKP 1604
Fly 1605 IQRILKYPLLLQQMRNLTDTRADEHVHLCEALKGMEKVAEHINEMQRIHEEYGAIFDHLFRQHQK 1669
Fly 1670 SCKQPIDLSPGDLLYYGGVEWLNISDFLGKIKKGLELHAMCFVFKSAVVFLCKERLRQKKKLMGV 1734
Fly 1735 SSKNATNEVEIIRYQVLIPVTEVQVRASSAKDMDSHFLWELIHLRSQLQRRSEKVYVLSNSTADF 1799
Fly 1800 RNAFLKTIRQIIRESVRNMSIPMKNFGGSSGSVSGHSSQGMGSMGY------PGNSQTLE----- 1853
Fly 1854 RPKQQITIVHGS----HTLGKPKKKSG---------SQRHSAGNIDYDNLSGSQEADDLPPSVGV 1905
Fly 1906 VHYASGHTHGQQMQPAGFRGRSKTVGDVTEITCSSPEPHQQQQQQQQQ 1953 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | |||
| RhoGEF | 1456..1647 | CDD:238091 | 41/192 (21%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 24/172 (14%) | ||
| PH | 1693..1812 | CDD:278594 | 16/118 (14%) | ||
| Net1 | NP_062645.2 | Necessary for nuclear localization | 1..74 | 10/51 (20%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..42 | 5/19 (26%) | |||
| Nuclear localization signal | 12..19 | ||||
| Nuclear localization signal | 66..72 | 1/5 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 127..151 | 6/23 (26%) | |||
| RhoGEF | 178..354 | CDD:214619 | 45/205 (22%) | ||
| PH_Net1 | 368..502 | CDD:270044 | 29/185 (16%) | ||
| PH | 387..501 | CDD:278594 | 25/158 (16%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 555..595 | 8/40 (20%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||