Protein Alignment sif and arhgef9b

DIOPT Version :9

• Sequence 1: NP_001261446.1
• Gene: sif / 43892
• FlyBaseID: FBgn0085447
• Length: 2734
• Species: Drosophila melanogaster
• Sequence 2: XP_021336708.1
• Gene: arhgef9b / 560923
• ZFINID: ZDB-GENE-030131-7745
• Length: 573
• Species: Danio rerio
• Alignment Length: 639
• Identity: 128/639 - (20%)
• Similarity: 199/639 - (31%)
• Gaps: 262/639 - (41%)

  Fly  1974 REPPPPPIRQPHLHHHSSDIERIDPGTKSEGEEDSQQGTIRPKATLGRTPNHLTLSTTSTL---- 2034
            |:.|..|.|:||        ..|.||                      .|:.|.||.|:.:
Zfish    76 RKAPSDPDRRPH--------SMILPG----------------------EPSFLKLSITNKVRNFK 110

  Fly  2035 -----SVGSTGSQARLIQSSHPPASYQPVLMKDLG------KPSPDESELES---------ESEV 2079
                 || ..|..:|:..|.:      .:.:||.|      |.|| .||.::         ....
Zfish   111 KLKSPSV-FKGKASRISDSKY------NIDLKDEGDDMYMCKDSP-SSEFKNVFKNKAKRHSFAG 167

  Fly  2080 HAAQVAASFNLSLGSSGSLFASDARDNQTQSRTQSQIHSLHPSPRQSPR------QSPRQSPKQD 2138
            |.|....||. .:..||:      .|| .|..|::.: |.|...:.|.|      ..|..|...:
Zfish   168 HTADFYCSFE-DIDPSGT------PDN-VQEETKNTV-SNHNGCKLSERVIYTKKSHPNFSNCNN 223

  Fly  2139 IEVIEIFESEAERLAASQQVAVVHQHPSDQARESGHK--QRRDRDRNPTETDATARFMDKHL--- 2198
            ..|||                     |.|...:...|  |||...|.....:...|...|..
Zfish   224 SSVIE---------------------PEDSCAKQSFKIPQRRRWSRGGDVLNYLRRISLKGKGSQ 267

  Fly  2199 ----SDLEQENLTDGTCD---------IVAYMESLREKA---------------FDPQDLAEDTG 2235
                |..|..|..|.|.|         :|..:.|..|::               |:  .:||...
Zfish   268 TLAESSFESMNTLDKTIDSDYGSVSFELVKDLNSAPEQSGVDGKSGHFRGLLRFFN--TVAETAM 330

  Fly  2236 DHQQNDSSLSP----EPQTIVENTQQT--VVVDIESPSRPATESDST--GNTTGPSERSGDETEE 2292
            ..:.:..|.||    :.|..:..|||:  ::.:...|.|...:.|::  |.:|.|.:
Zfish   331 KWRNSSRSFSPPEGQQSQLDLRKTQQSGELIQNTPLPVRSEHKDDTSVHGKSTLPLD-------- 387

  Fly  2293 EATTSSLASHIVVIDKKVDKIFKAKSPERPASTKVKGGRRQIYISPDRCKSQGSSPVRIIKI--- 2354
                  :...:..::.|||                             |     ||..::|.
Zfish   388 ------MCKVVSTVNDKVD-----------------------------C-----SPPVVLKAWRT 412

  Fly  2355 --KSPRTSLSDQGKRLSVCSSRDNSQDRLSAGRRT-----PSPR-RSSEGGGILKHTTG------ 2405
              .|||.|       .|:|::.|.||.::|:...:     ..|| ..:|...:|||..|
Zfish   413 CPDSPRDS-------NSLCNNSDESQSQISSTHISLATIESHPRYEEAEPPALLKHLPGKTEDEN 470

  Fly  2406 ------------PD---------PGILKPPSSPAKSKSPDRSCLKKGGPSHVCSVE--TLSPRVS 2447
                        |:         ||  |.|:.| ..|:..:.|.....|:.:.::|  ||:..::
Zfish   471 QDTCMDRKKFICPEDIFKTLSRPPG--KSPADP-PLKALLQRCCSLPLPNTLSALEPITLTHVLT 532

  Fly  2448 PRGSMDHLSPDRGMTSSSCLRHSPRSSFDSHGESDHNLDVPHGSRKRSMSAHGS 2501
            |        |.:.:..||.||....|:               ||.:|.:...||
Zfish   533 P--------PAKSIAKSSILRMRNSST---------------GSNRRKLFRPGS 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sif	NP_001261446.1	WH1	35..144	CDD:214674
		PH1_Tiam1_2	860..985	CDD:269937
		PH	873..974	CDD:278594
		TIAM1_RBD	1141..1219	CDD:176413
		PDZ_signaling	1221..1308	CDD:238492
		RhoGEF	1456..1647	CDD:238091
		PH2_Tiam1_2	1650..1823	CDD:269957
		PH	1693..1812	CDD:278594
arhgef9b	XP_021336708.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3519
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1291
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840