| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_999983.1 | Gene: | arhgef18a / 407987 | ZFINID: | ZDB-GENE-040516-14 | Length: | 940 | Species: | Danio rerio |
| Alignment Length: | 1232 | Identity: | 250/1232 - (20%) |
|---|---|---|---|
| Similarity: | 410/1232 - (33%) | Gaps: | 435/1232 - (35%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1404 AKPTSRTSSFEIEN-------------LLKTAEQETRK-SSPTGSVTSSVSTTALTP---SRQLT 1451
Fly 1452 DAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQN 1516
Fly 1517 LE-ESLD-LEPDFNKFEHC----GQFRNVLFA--IGSAFLYYVNHFKLYSSFCASHSKAQKVLHP 1573
Fly 1574 NEGNHALQEFLAARNPKQQHSSTLESYLIKPI-------------------QRILKYPLLLQQMR 1619
Fly 1620 NLTDTRADEHVHLCEALKG-------MEKVAEHINEMQ---RIHE---------EYGAIFDHLFR 1665
Fly 1666 QHQKSCKQPIDLSPG--DLLYYGGVEW-----------------LNISD-FLGKIKKGLELHAMC 1710
Fly 1711 FVFKSAVVFLCK----ERLRQKKKLMGVSSKNATNEVEIIRYQVLIPVTEVQVRASSAKDMD--S 1769
Fly 1770 HFLWELIHLRSQLQRRSEKVYVLSNSTADFRNAFL---KTIRQIIRESVRNMSIPMKNFGGSSGS 1831
Fly 1832 VSGHSSQGMGSMGYPGNSQTLERPKQQITIVHGSHTL-GKPKKKSGSQRHSAGNI-DYDNLSG-- 1892
Fly 1893 ----------SQEADDL---PPSVGVVHYASGHTHGQQMQPA-GFRGRSKTVGDVTEITCSSPEP 1943
Fly 1944 HQQQQQQQQQQQQLMQQGHAHAHPHPHPHPREPPPPPIRQPHLHHHSSDIERIDPGTKSEGEE-- 2006
Fly 2007 -DSQQGTIRPKATLGRTPNHLTLSTTSTLSVGSTGSQARLIQSSHPPASYQPVLMKDLGKPSPDE 2070
Fly 2071 SELESESEVHAAQVAASFNLSLGSSGSLFASDAR-DNQTQSRTQSQIHSLHPSPRQSPRQSPRQS 2134
Fly 2135 PKQDIEVIEIFESEAERLAASQQVAVVHQHPSDQARESGHKQRRDRDRNPTETDATARFMDKHLS 2199
Fly 2200 DLEQENLTDGTCDIVAYMESLR--EKAFDPQDLAEDTGDHQQNDSSLSPEPQTIVENTQQTV--- 2259
Fly 2260 --VVDIESPSRPATESDSTGNTTGPSERSG-DETEEEATTSSLASHIVVIDKKVDKIFKAKSPER 2321
Fly 2322 PASTKVKGGRRQIYISPDRCKSQGSSPVRIIKIKSPRTSLSDQGKRLSVCSSRDNSQDRLSAGRR 2386
Fly 2387 TPSPRRSSEGGGI-LKHTTGPDPGILKPPSSPAKSKSPDRSCLKKGGPSHVCSVETLSPRVSPRG 2450
Fly 2451 SMDHLSPD----RGMTSSSCLRHSPRS------SFDSHGESDHNLDVPHGSRKRSMSAHGSF 2502 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | |||
| RhoGEF | 1456..1647 | CDD:238091 | 53/224 (24%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 37/213 (17%) | ||
| PH | 1693..1812 | CDD:278594 | 25/128 (20%) | ||
| arhgef18a | NP_999983.1 | RhoGEF | 74..266 | CDD:279015 | 52/218 (24%) |
| PH-like | 307..427 | CDD:302622 | 25/134 (19%) | ||
| DUF4200 | 650..747 | CDD:290574 | 31/147 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| ZFIN | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||