| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001097184.2 | Gene: | RtGEF / 35306 | FlyBaseID: | FBgn0015803 | Length: | 1310 | Species: | Drosophila melanogaster |
| Alignment Length: | 1456 | Identity: | 286/1456 - (19%) |
|---|---|---|---|
| Similarity: | 483/1456 - (33%) | Gaps: | 420/1456 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1441 TTALTPSRQLTDAEKLRKVVM-ELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIH 1504
Fly 1505 EIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHF-KLYSSFCASHSKAQ 1568
Fly 1569 KVLHPNEGNHALQEFLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQM-RNLTDTRADEHVHL 1632
Fly 1633 CEALKGMEKVAEHINEMQR---IHEEYGAIFDHLFRQHQKSCKQPIDLSPGDLLYYGGVEWLNIS 1694
Fly 1695 DF--LGKIKKGLELHAMCFV-FKSAVVFLCKERLRQKKKLMGVSSKNATNEVEIIRYQVLIPVTE 1756
Fly 1757 VQVRASSAKDMDSHFLWELIHLRSQLQRRSEKVYVLSNSTADFRNAFLKTIRQIIRESVRNMSIP 1821
Fly 1822 M------KNFGGSS-GSV-SGHSSQGMGSMGY-------------PGNSQTLERPKQQITIVHGS 1865
Fly 1866 HTLGKPKK----------KSGSQR----------HSAGNIDYDNLS--------GSQEADDLPPS 1902
Fly 1903 VGVVHYASGHTHGQQMQPAGFRGRSKTVGDVTE----ITCSSPEPHQQQQQQQQQQQQLMQQGHA 1963
Fly 1964 HAHPHPHPHPREPPPPPIRQPHLHHHSSDIERIDPGTKSE-------GEEDSQQGT--IRPKATL 2019
Fly 2020 GRTPNHLTLSTTSTLSVGSTGSQARLIQSSHPPASYQPVLMKDLGKPSPDESELESE-SEVHAAQ 2083
Fly 2084 VAASF----NLSLGSSGSLFASDARDNQTQSRTQSQIHSLHPSPRQSPRQSPRQSPKQDIEVIEI 2144
Fly 2145 FESEAERLAASQQVAVVHQHPSDQARESGHKQRRDRDRNPTETDATARFM---DKHLSDLEQENL 2206
Fly 2207 TDGTCDIVAYMESLREKAFDPQDLAEDTGDHQQND---SSLSPEPQTIVENTQQTVVVDIESPSR 2268
Fly 2269 PATESDSTGNTTGPSERSGDETEEEATTSSLASHIVVIDKKVDKIFKAKSPERPASTKVKGGRRQ 2333
Fly 2334 IYISPDRCKSQGSSPVRIIKIKSPRTSLSDQGKRLSVCSSRDNSQDRLSAGRRTPSPRRSSEGGG 2398
Fly 2399 ILKHTTGPDP---------------------------------GILKPPSS----------PAKS 2420
Fly 2421 KSPDRSCLKKGGPSHVCS----VETLSPRVSPRGSMDHLS---PDRGM--TSSSCLRHSPRSSFD 2476
Fly 2477 S----HGESDHNL--DVPHG---SRKRSMSAHGSFETGT------RPRAQETYQYYPVYDN--QT 2524
Fly 2525 CSDHYVAAAPTGRYGGGTSSRSRLSKSLERSTSRDSTTTSSSYGHRAYGVSPDRNYVV------- 2582
Fly 2583 ----FSSGPLRSQSAENTFSS---QPIYDPLPRHPPQPLHQPPMHHQQQQQQQQQQQYMSYAPEM 2640
Fly 2641 GGYTGCQHDPQGGYQLSSSAPEYTTCIDCLYQKRPSXHKSRVRQS---RTRKKTPRGMVVVSAQP 2702
Fly 2703 TATGG----IGFVP---EMGSSEAPG 2721 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | |||
| RhoGEF | 1456..1647 | CDD:238091 | 50/193 (26%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 33/184 (18%) | ||
| PH | 1693..1812 | CDD:278594 | 21/121 (17%) | ||
| RtGEF | NP_001097184.2 | SH3_PIX | 6..58 | CDD:212810 | |
| RhoGEF | 79..249 | CDD:238091 | 53/208 (25%) | ||
| PH_Cool_Pix | 281..376 | CDD:269932 | 21/125 (17%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C45462289 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.840 | |||||