| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_006497917.1 | Gene: | Vav2 / 22325 | MGIID: | 102718 | Length: | 878 | Species: | Mus musculus |
| Alignment Length: | 590 | Identity: | 124/590 - (21%) |
|---|---|---|---|
| Similarity: | 223/590 - (37%) | Gaps: | 173/590 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1450 LTDAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFL 1514
Fly 1515 QNLEESLDLEPDFNKFEHCGQFRNVLFAIGS----AFLYYVNHFKLYSSFCASHSKAQKVLHPNE 1575
Fly 1576 GNHALQEFLAARNPKQQH-----------SSTLESYLIKPIQRILKYPLLLQQMRNLTDTRADEH 1629
Fly 1630 VHLCEALKGMEKVAEHINEMQRIHE------EYGAIFDHLFRQHQKSCKQPIDLSPGDLLYYGGV 1688
Fly 1689 EWLNISDFLGKIKKGLELHAMCFVFKSAVVFLCKER--LRQKKKLMGVSSKNATNEVEIIRYQVL 1751
Fly 1752 IPVTEVQVRASSAKDMDSHFLWE----LIHLRSQLQRRSEKVYVLSNSTADFRNAFLKTIRQIIR 1812
Fly 1813 ESVRNMSIPMKNFGGSSGSVSGHSSQ------------------GMGSMGYPGNSQTLERPKQQI 1859
Fly 1860 TIVHGSHTLGKPKKKSGSQRHSAGNIDYDNLSGSQEADDLPPSVGVVHYASGHTHGQQMQPAGFR 1924
Fly 1925 GRSKTV-----GDVTEITCSSPEPHQQQQQQQQQQQQLMQQGHAHAHP----HPHPHPREPPP-- 1978
Fly 1979 PPIRQ 1983 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | |||
| RhoGEF | 1456..1647 | CDD:238091 | 49/205 (24%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 31/184 (17%) | ||
| PH | 1693..1812 | CDD:278594 | 22/124 (18%) | ||
| Vav2 | XP_006497917.1 | CAMSAP_CH | 18..103 | CDD:314792 | |
| RhoGEF | 202..375 | CDD:214619 | 50/203 (25%) | ||
| PH_Vav | 389..516 | CDD:269930 | 30/176 (17%) | ||
| C1 | 524..571 | CDD:237996 | 7/53 (13%) | ||
| SH3_VAV2_1 | 590..649 | CDD:212913 | 16/76 (21%) | ||
| SH2_Vav2 | 667..769 | CDD:198269 | |||
| SH3_VAV2_2 | 819..876 | CDD:212910 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1291 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||