| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_035821.3 | Gene: | Vav1 / 22324 | MGIID: | 98923 | Length: | 845 | Species: | Mus musculus |
| Alignment Length: | 612 | Identity: | 126/612 - (20%) |
|---|---|---|---|
| Similarity: | 231/612 - (37%) | Gaps: | 151/612 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1414 EIENLLKTAEQETRKSSPTGSVTSSVSTTALTPSRQLTDAEKLRKVVMELVDTERTYVKHLNNLL 1478
Fly 1479 EHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAI 1543
Fly 1544 GSAFLYYVNHFKLYSSFCASHSKAQKVLHPNEGNHALQEFLAARNPKQ-------QHSS----TL 1597
Fly 1598 ESYLIKPIQRILKYPLLLQQM-RNLTDTRADEHVHLCEALKGMEKVAEHINEMQRIHEEYGAI-- 1659
Fly 1660 ----FDHLFRQHQKSCKQPIDLSPGDLLYYGGVEWLNISDFLGKIKKGLELHAMCFVFKSAVVFL 1720
Fly 1721 CKERLRQKKKLMGVSSKNATNEVEIIRYQVLIPVT--EVQVRASSAKDMDSHFLWELIHLRSQLQ 1783
Fly 1784 RRSEKVYVLSNSTADFRNAFLKTIRQIIRESVRNMSIPMKNFGGSSGSVSGHSSQ---------- 1838
Fly 1839 --------GMGSMGY-------PGNSQTLER--PKQQITIVHG---SHTLGKPKKKSGSQRHSAG 1883
Fly 1884 NIDYDNLSGSQEADDLPPSVGVVHYASGHTHGQQMQPAGFRGRSKTVGDVTEITCSSPEPHQQQQ 1948
Fly 1949 QQQQQQQQLMQQGHAHAHPHPHPHPRE 1975 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | |||
| RhoGEF | 1456..1647 | CDD:238091 | 53/202 (26%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 28/180 (16%) | ||
| PH | 1693..1812 | CDD:278594 | 20/120 (17%) | ||
| Vav1 | NP_035821.3 | CH | 18..102 | CDD:320720 | |
| RhoGEF | 195..371 | CDD:238091 | 53/202 (26%) | ||
| PH_Vav | 385..508 | CDD:269930 | 26/173 (15%) | ||
| C1_1 | 516..567 | CDD:278556 | 9/54 (17%) | ||
| SH3_VAV1_1 | 596..658 | CDD:212912 | 15/78 (19%) | ||
| SH2_Vav1 | 665..767 | CDD:198268 | 0/1 (0%) | ||
| SH3_VAV1_2 | 786..839 | CDD:212909 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1291 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||