| Sequence 1: | NP_001261446.1 | Gene: | sif / 43892 | FlyBaseID: | FBgn0085447 | Length: | 2734 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_694945.2 | Gene: | ARHGEF19 / 128272 | HGNCID: | 26604 | Length: | 802 | Species: | Homo sapiens |
| Alignment Length: | 539 | Identity: | 118/539 - (21%) |
|---|---|---|---|
| Similarity: | 195/539 - (36%) | Gaps: | 183/539 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1293 LESVLQEEQSLSMMMRSSRTEPPDLVGIMRVTDDMIDSLVCPPPPTDPPVMSEEMITGLIVPAPG 1357
Fly 1358 WNGTSKDLYSPEAESSPATSFVDPAAMAAQLAVGGVGGVVVGGLGVAKPTSRTSSFEIENLLKTA 1422
Fly 1423 EQETRKSSPTGSVTSSVSTTALTPSRQLTDAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKR 1487
Fly 1488 ETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKF-------EHCGQFRNVLFAIGS 1545
Fly 1546 AFLYYVNH----FKLYSSFCASHSKAQKVLHPNEGNHALQEFLAARNPKQQHSSTLESYLIKPIQ 1606
Fly 1607 RILKYPLLLQQMRNLT---------DTRA----DEHVHLCEA-LKGMEKVAEHINEMQRIHEEYG 1657
Fly 1658 AIFD------HLFRQHQKSCKQPIDLSPGDLLYYGGVEWLNISDFLGKIK---KGLELHAMCFVF 1713
Fly 1714 KSAVVFLCKERLRQKKKLMGVSSKNATNEVEIIRYQVLI--PVTEVQVRASSAK--DMDSH-FLW 1773
Fly 1774 ELI---HLRSQ--LQRRSE 1787 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sif | NP_001261446.1 | WH1 | 35..144 | CDD:214674 | |
| PH1_Tiam1_2 | 860..985 | CDD:269937 | |||
| PH | 873..974 | CDD:278594 | |||
| TIAM1_RBD | 1141..1219 | CDD:176413 | |||
| PDZ_signaling | 1221..1308 | CDD:238492 | 6/14 (43%) | ||
| RhoGEF | 1456..1647 | CDD:238091 | 53/215 (25%) | ||
| PH2_Tiam1_2 | 1650..1823 | CDD:269957 | 35/157 (22%) | ||
| PH | 1693..1812 | CDD:278594 | 25/108 (23%) | ||
| ARHGEF19 | NP_694945.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
| Herpes_ICP4_C | 10..>353 | CDD:332854 | 24/120 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 84..138 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 171..190 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 222..283 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 306..342 | 14/93 (15%) | |||
| RhoGEF | 382..558 | CDD:306973 | 48/196 (24%) | ||
| PH_ephexin | 580..706 | CDD:269929 | 33/152 (22%) | ||
| SH3_ARHGEF5_19 | 719..773 | CDD:212873 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||