Protein Alignment sif and AKAP13

DIOPT Version :9

• Sequence 1: NP_001261446.1
• Gene: sif / 43892
• FlyBaseID: FBgn0085447
• Length: 2734
• Species: Drosophila melanogaster
• Sequence 2: NP_006729.4
• Gene: AKAP13 / 11214
• HGNCID: 371
• Length: 2817
• Species: Homo sapiens
• Identity: / - (0%)
• Similarity: / - (0%)
• Gaps: / - (0%)

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sif	NP_001261446.1	WH1	35..144	CDD:214674
		PH1_Tiam1_2	860..985	CDD:269937
		PH	873..974	CDD:278594
		TIAM1_RBD	1141..1219	CDD:176413
		PDZ_signaling	1221..1308	CDD:238492
		RhoGEF	1456..1647	CDD:238091
		PH2_Tiam1_2	1650..1823	CDD:269957
		PH	1693..1812	CDD:278594
AKAP13	NP_006729.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..400
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	415..439
		Important for interaction with PRKAR2A	494..516
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	539..585
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	632..653
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	690..726
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	805..856
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	939..965
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1431..1455
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1467..1542
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1605..1642
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1759..1797
		C1	1796..1842	CDD:294036
		Interaction with ESR1. /evidence=ECO:0000269|PubMed:9627117	1923..2817
		RhoGEF	1999..2193	CDD:238091
		PH_AKAP13	2236..2338	CDD:275427
		PH	2236..2336	CDD:278594
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2470..2506
		RILP-like	<2630..>2700	CDD:304877
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2669..2817

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910