Protein Alignment Ret and ATN1

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_189393.1
• Gene: ATN1 / 822378
• AraportID: AT3G27560
• Length: 356
• Species: Arabidopsis thaliana
• Alignment Length: 306
• Identity: 92/306 - (30%)
• Similarity: 147/306 - (48%)
• Gaps: 54/306 - (17%)

  Fly   753 SGF----RFESGDAKWEFPREKLQLDTVLGEGEFGQVLKG-FATEIAGLPGITTVAVKMLKKGSN 812
            |||    .||. |.||......|.:...:|||...:|.:| :..:        |||:|::|:|.:
plant     5 SGFYSNEEFEL-DPKWLVDPRHLFVGPKIGEGAHAKVYEGKYRNQ--------TVAIKIIKRGES 60

  Fly   813 SVEYM----ALLSEFQLLQEVSHPNVIKLLGACTSSEAPLLII--EYARYGSLRSYLRLSRKIEC 871
            ..|..    ....|..:|.:|.|.|::|.:|||   :.|:::|  |....|:||.||...|.
plant    61 PEEIAKRDNRFAREIAMLSKVQHKNLVKFIGAC---KEPMMVIVTELLLGGTLRKYLVSLRP--- 119

  Fly   872 AGVDFADGVEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNVLL-ADGKICKISDFGLTRD 935
                     :.:::::.:.||..|.:.|..|....::||||...|::| ||.|..|::||||.|
plant   120 ---------KRLDIRLAVGFALDIARAMECLHSHGIIHRDLKPENLILSADHKTVKLADFGLAR- 174

  Fly   936 VYEDDAYLKRSRDRVPVKWMAPESLA---------DHVYTSKSDVWSFGVLCWELITLGASPYPG 991
              |:......:.:....:|||||..:         .| |..|.|.:||.::.|||| |...|:.|
plant   175 --EESLTEMMTAETGTYRWMAPELYSTVTLRQGEKKH-YNHKVDAYSFAIVLWELI-LNKLPFEG 235

  Fly   992 IAPQNLWSLLKTGYRMDRP--ENCSEAVYSIVRTCWADEPNGRPSF 1035
            ::  ||.:.....::..||  |:....:..||.:||.::||.||:|
plant   236 MS--NLQAAYAAAFKNLRPSAEDLPGDLEMIVTSCWKEDPNERPNF 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	84/285 (29%)
ATN1	NP_189393.1	STKc_MAP3K-like	32..286	CDD:270901	83/278 (30%)