Protein Alignment Ret and fynb

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: XP_068071652.2
• Gene: fynb / 574422
• ZFINID: ZDB-GENE-050706-89
• Length: 596
• Species: Danio rerio
• Alignment Length: 361
• Identity: 119/361 - (32%)
• Similarity: 179/361 - (49%)
• Gaps: 52/361 - (14%)

  Fly   710 LLCLLIAQRKMLQRRLGKQSMTT--------SSKQALPESGGGDFALMPLQS--GFRFE------ 758
            |.|.|:........||...|:.|        .|.|.:...|.|.|..:.::|  |..|.
Zfish   245 LCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMESADGLCFNLTGVCM 309

  Fly   759 ---------SGDAKWEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVKMLKKGSNSV 814
                     |.|: ||..||.|.||..||.|.|..|..|...      |.|.||:|.||.|:.|.
Zfish   310 VYTPDTVGLSHDS-WEIARESLTLDMKLGAGCFADVWYGTWN------GNTKVAIKTLKPGTMSP 367

  Fly   815 EYMALLSEFQLLQEVSHPNVIKLLGACTSSEAPLLII-EYARYGSLRSYLRLSRKIECAGVDFAD 878
            |  :.|.|.|:::::.|..:::|....  ||.|:.|: ||...|||..:|:             |
Zfish   368 E--SFLEEAQIMKKLRHDKLVQLYAVV--SEEPIYIVTEYMGKGSLLDFLK-------------D 415

  Fly   879 GV-EPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAY 942
            |. ..:.:..::..|.|:..||||:..:..:||||.:.|:|:.|..:|||:||||.| :.||:.|
Zfish   416 GEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLAR-LIEDNEY 479

  Fly   943 LKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRM 1007
            ..|...:.|:||.|||:.....:|.||||||||:|..||:|.|..||||:..:.:...::.||||
Zfish   480 TARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRM 544

  Fly  1008 DRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFE 1043
            ..|::|..:::.::..||..:...||:|::|.:..|
Zfish   545 QCPQDCPSSLHELMVQCWKKDAEERPTFEYLQAFLE 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	98/276 (36%)
fynb	XP_068071652.2	None