Protein Alignment Ret and ptk6a

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: XP_682778.7
• Gene: ptk6a / 555232
• ZFINID: ZDB-GENE-081105-117
• Length: 510
• Species: Danio rerio
• Alignment Length: 284
• Identity: 107/284 - (37%)
• Similarity: 158/284 - (55%)
• Gaps: 28/284 - (9%)

  Fly   764 WEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQE 828
            ||.|:|:..|:..||:|.|..|.:|      ...|:..||:|:||  ::|:.:...:.|.|:|::
Zfish   236 WELPKEEFTLEEELGKGFFADVYRG------KWKGMVNVAIKILK--NDSINHREFMLETQILKK 292

  Fly   829 VSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVDFADGVEPVNVKMVLTFAW 893
            :.|.::|.|...||||....:|.|....|.|.|.|:        |.:..|    :|.:|:...|.
Zfish   293 LRHKHLIALFAVCTSSSPFYIITELMEKGDLLSLLK--------GKEGQD----LNAQMLTEMAS 345

  Fly   894 QICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRD-RVPVKWMAP 957
            |:..|||||.|...:||||||||||:....|||::|.||.|.|.|.   :..|.| ::|.||.||
Zfish   346 QVADGMAYLEEQNSIHRDLAARNVLVGANYICKVADLGLARIVKES---VYSSEDAQIPYKWSAP 407

  Fly   958 ESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVR 1022
            |:::...:::||||||||||.:|:.|.|..|||..:...:::::.:||||..|.||...:|.|:.
Zfish   408 EAISHGRFSNKSDVWSFGVLLYEMFTYGGVPYPAFSNIEVYNMITSGYRMPAPPNCPSHIYDIML 472

  Fly  1023 TCWADEPNGRPSFKFLASEFEKLL 1046
            .||......||.|    ||..:||
Zfish   473 MCWRYSAEERPDF----SELLRLL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	103/278 (37%)
ptk6a	XP_682778.7	SH3_Brk	57..114	CDD:212781
		SH2	121..208	CDD:214585
		Protein Kinases, catalytic domain	236..488	CDD:473864	104/278 (37%)