Protein Alignment Ret and Src64B

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 107/286 - (37%)
• Similarity: 154/286 - (53%)
• Gaps: 29/286 - (10%)

  Fly   763 KWEFPREKLQLDTVLGEGEFGQVLKG-FATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLL 826
            |:|.||.::||...||.|.||:|..| :...|       .||||.|::|:.|.  .|.|.|..::
  Fly   277 KYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSI-------DVAVKTLREGTMST--AAFLQEAAIM 332

  Fly   827 QEVSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAG--VDFADGVEPVNVKMVL 889
            ::..|..::.|...|:..|...::.||...|||..:||     |..|  :.|.|         ::
  Fly   333 KKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLR-----EGDGRYLHFED---------LI 383

  Fly   890 TFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKW 954
            ..|.|:..||.||...:|:||||||||||:.:..:.||.||||.| |..||.|..:...|.||||
  Fly   384 YIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLAR-VIADDEYCPKQGSRFPVKW 447

  Fly   955 MAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPEN--CSEAV 1017
            .|||::....::.||||||:|:|..||.|.|..||||:..:.:...::.|:||.:|.|  ..:.:
  Fly   448 TAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNI 512

  Fly  1018 YSIVRTCWADEPNGRPSFKFLASEFE 1043
            |.::..||...|..||:|:||...||
  Fly   513 YQLLLQCWDAVPEKRPTFEFLNHYFE 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	103/279 (37%)
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827
		PTKc_Src_like	289..538	CDD:270630	99/272 (36%)
		SH3_Src_like	99..150	CDD:212779