Protein Alignment Ret and Cad96Ca

DIOPT Version :9

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Alignment Length: 905
• Identity: 232/905 - (25%)
• Similarity: 344/905 - (38%)
• Gaps: 300/905 - (33%)

  Fly   302 LVYAVHNDSHGLFRPDCHAYEADHTGRPHTIVSCQLRFSRNGVFRETPYCVSLEARDLTIVSRVD 366
            :||..||                |..|   |:.|:.:.:.   :|.....:::.....|:||.:.
  Fly     1 MVYHHHN----------------HESR---IIHCRKQLTS---WRRRSLLLTIIVVTATVVSLIS 43

  Fly   367 AMSATANVCYHINLSKLHESEQELPQALPLRARQHRIFESEEF------------NGD------- 412
            ..:...|              |..|..|.:|.|..||.|:|:.            :||
  Fly    44 QEAEAHN--------------QNAPPILYVRERNWRISETEKVGQIIDRVRAEDPDGDDLIFGIE 94

  Fly   413 ------SAGRSLSPP-----TVDYDKDV-----SVYRSAASNFRVVQPDSFLDLMRLRSIRFDIV 461
                  ......|||     .:|.:..|     |:...|..||.:.
  Fly    95 PRFSLPGGENDASPPEKIPFQIDRETGVVTLNESLAGRAGQNFLIY------------------- 140

  Fly   462 EDKLGAFGITSTSGIVFVKNPQVLEEAPETIYFLNVTWIDQQRLSHVRVINVHLVHGRPENTSCE 526
                    ||.|.|....||.          .|:|:.                   |..||:|
  Fly   141 --------ITVTDGSYTAKNE----------VFINIL-------------------GERENSS-- 166

  Fly   527 LKVKSRSQTCAQIKYQSQCVRYCGLATGGGSCQWRGSNSAMFGTRYGSC---------VPESRYC 582
               ..|.||..     |..|.                |.:.|..|:...         :|.||
  Fly   167 ---GYRPQTSI-----SNVVH----------------NISQFLPRFDQLPGVQSIRNGLPNSR-- 205

  Fly   583 PDHVCDPLEELNPMACPQDCTPAGRIVGPHSSN-ENKRGIYSASGTCICEDNGKCSCAPLDEEP- 645
            |.....|:.:.|....|    |.|....|...| ...||          |.:|:      :|:|
  Fly   206 PGGWYPPVPQNNIFGPP----PFGNNYPPPPPNIPGVRG----------EQSGE------EEQPD 250

  Fly   646 -----------KMKKPRKR--------KNETEAEPLLGVRRGTP-------PNQP-----LQDPM 679
                       ....|:.|        .|.|..|..:.....||       .:.|     |:...
  Fly   251 EEVTPTTPVRISSTTPKSRTKLTPITANNSTRVESAIPAETTTPSGGHHNNSSSPITIFSLKSGT 315

  Fly   680 LLGVLNVAGFECDRSCMFFVITCPLLFVLL--LLCLLIAQRKMLQRR--LGKQS--------MTT 732
            :..|:.|.|        |||....||..|.  .||.:....|..:.:  |.|:|        :|.
  Fly   316 IPIVVTVGG--------FFVAIAVLLAYLCRRRLCAISRTLKKTKEKEELAKKSNQSQLSSTLTD 372

  Fly   733 SSKQAL-----------------------------------------------PESG-------- 742
            .|:.::                                               |.:|
  Fly   373 DSRNSMVMQQWQGPVAFANRYVPWERDQQMGIATSQLSTGVTNGGVSSPGVPSPGTGEPGSNLGP 437

  Fly   743 ----GGDFALMPLQSGFRFESGDAKWEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVA 803
                ||..:....::.|..|:...:|||||.:|:...:||||.||||.:..||.|.|..||||||
  Fly   438 GCLTGGAGSSGAPENAFAGEANCDRWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVA 502

  Fly   804 VKMLKKGSNSVEYMALLSEFQLLQEVS-HPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSR 867
            ||.||:.:..|:...||||.::::.:. |.||:.|||.||..:...:|:||...|.|::|||.||
  Fly   503 VKTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSR 567

  Fly   868 KIECAGVDFADGVEPVNVKMVLT-FAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFG 931
            .....|  ...|...|.....|| |.:|:.|||.||:...::||||||||:|:.|...||::|||
  Fly   568 AERHYG--NTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFG 630

  Fly   932 LTRDVYEDDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQN 996
            ..|||.....|.::|..::|::|||.|||.|::::.|||:||||:|.||::|||::|||||:..:
  Fly   631 FARDVITSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAAD 695

  Fly   997 LWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKLLGNNAKYIDLE 1056
            :...::.|||:::||:|...:|:|:..||:.:|..||.|..:....:|||.....||:||
  Fly   696 VMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKLLHTEMDYIELE 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	PKc_like	770..1049	CDD:304357	121/280 (43%)
		TyrKc	771..1042	CDD:197581	118/272 (43%)
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637	24/154 (16%)
		STYKc	470..741	CDD:214568	118/272 (43%)
		PTKc	474..742	CDD:270623	117/269 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455301
Domainoid	1	1.000	165	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D52607at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950