Sequence 1: | NP_477044.1 | Gene: | Ret / 43875 | FlyBaseID: | FBgn0011829 | Length: | 1235 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_002244.1 | Gene: | KDR / 3791 | HGNCID: | 6307 | Length: | 1356 | Species: | Homo sapiens |
Alignment Length: | 1354 | Identity: | 321/1354 - (23%) |
---|---|---|---|
Similarity: | 523/1354 - (38%) | Gaps: | 376/1354 - (27%) |
- Green bases have known domain annotations that are detailed below.
Fly 39 INEESESIFSK---IP------LAQFQVLRMEDNRLASDYLYSLE-QNPLL-RINSSSGEIYMRT 92
Fly 93 DYRSPNSSATFLVTAFPRDQPDHELLNVSHLSLEVTPQ-PLEEYCSELEHICFWSSAQYTIAESH 156
Fly 157 GPYRRKDFFEPVLIGALNSRAAKYLCPHVSLE-YSLNAGSSHFVLKQNRLYTRQTLDHDELNGLN 220
Fly 221 AKAGQLQARITCTV----------------------KLSSRD--------QRKFSRILDIKLLDR 255
Fly 256 NDNG--------PKLQESSSKFDFYLEQPY--FQADEEAGKKVIYVDKDTLEANAHLVYAVHNDS 310
Fly 311 HGLFRPDCHAY------EADHT---GRPHTIVSCQLRFSRN-GVFRETP-------YCVSL---- 354
Fly 355 --EARDLTIVSRVDA------MSATANVC-----YHINLSKLHESE--QELPQAL----PLRARQ 400
Fly 401 HRIFESEEFNGDSAGRSLSPPTVDY------DKDVSVYRSAASNFRVVQPDSFLDLMRLRSIRFD 459
Fly 460 IVEDKLG------AFGITSTSGIVFVKNPQVLEEAPETIY-------FLNVTW--IDQQRLS-HV 508
Fly 509 RVINVHLVHGRPENTSCELKVKSRSQTCAQIKYQSQCVRYCGLATGGGSCQWRGSNSAMFGTRYG 573
Fly 574 SCVPESRYCPDHVCDPLEELNPMACPQDCTPAGRIVGPHSSNENKRGIYSASGTCICEDNGKCSC 638
Fly 639 APLDEEPKMKKPRKRKNETEAEPL----------LGVRRGTPPNQPLQDPMLLGVLNVAGFECDR 693
Fly 694 SCMFFVI------------------TCPLLFVLLLLCLLIAQRKMLQRRLGKQSMTTSSKQALPE 740
Fly 741 SGGGDFALMPLQSGF-----------------RFESGDAKWEFPREKLQLDTVLGEGEFGQVLKG 788
Fly 789 FATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEVSHP-NVIKLLGACTSSEAPLL-II 851
Fly 852 EYARYGSLRSYLRLSRK----IECAGVDFADGVE-----PVNVKM-------------------- 887
Fly 888 -----------------------VLTFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISD 929
Fly 930 FGLTRDVYEDDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGI-A 993
Fly 994 PQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKLLGNNAK-----YI 1053
Fly 1054 DLETNAVSNPLYCGDDS--ALITTELG--EPESLQHLWSPPKIAYDIHDQATSYDQS--EEEMPV 1112
Fly 1113 TSTAPPGYDLPRPLL------DATANGQVLRYENDLRFPLNIRKSSCTPSYSNM 1160 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Ret | NP_477044.1 | PKc_like | 770..1049 | CDD:304357 | 126/333 (38%) |
TyrKc | 771..1042 | CDD:197581 | 124/325 (38%) | ||
KDR | NP_002244.1 | Ig | 41..109 | CDD:299845 | 7/32 (22%) |
IG_like | 231..324 | CDD:214653 | 19/113 (17%) | ||
Ig1_VEGFR | 239..326 | CDD:143270 | 16/87 (18%) | ||
IG_like | 340..417 | CDD:214653 | 18/86 (21%) | ||
Ig2_VEGFR-2 | 348..417 | CDD:143272 | 18/78 (23%) | ||
Ig_2 | 551..661 | CDD:290606 | 21/124 (17%) | ||
IG | 565..661 | CDD:214652 | 18/110 (16%) | ||
I-set | 667..754 | CDD:254352 | 23/114 (20%) | ||
IGc2 | 680..744 | CDD:197706 | 13/72 (18%) | ||
PTKc_VEGFR2 | 826..1167 | CDD:270681 | 132/340 (39%) | ||
Pkinase_Tyr | 834..1160 | CDD:285015 | 124/325 (38%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1274..1318 | 4/13 (31%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |