Sequence 1: | NP_477044.1 | Gene: | Ret / 43875 | FlyBaseID: | FBgn0011829 | Length: | 1235 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_476759.1 | Gene: | Egfr / 37455 | FlyBaseID: | FBgn0003731 | Length: | 1426 | Species: | Drosophila melanogaster |
Alignment Length: | 1478 | Identity: | 304/1478 - (20%) |
---|---|---|---|
Similarity: | 496/1478 - (33%) | Gaps: | 516/1478 - (34%) |
- Green bases have known domain annotations that are detailed below.
Fly 20 HCAAVDVYFPTTSV-----KFNMPINEESESIFSKIPLAQFQVLRMEDNRLASDYLYSLEQNPLL 79
Fly 80 ---------RINSSSGEIYMRTDYRSPNSSATFLVTAFPRDQPD-HELLNVSH------------ 122
Fly 123 -LSLEVTPQ--------PLEEYCSELEHICFWSSAQYTIAESHGPYRR-----KDFFEPVLIGAL 173
Fly 174 NSRAAKYLCPHVS--------LE------YSLNAG-----SSHFVLKQNRLYTRQTLDHDEL--- 216
Fly 217 ------NGLNAK---------AGQLQARITCTVKLSSRDQRKFSRILD--IKLLDRNDNGPKLQE 264
Fly 265 SSSKFDFYLEQPYFQADEEAGKKVIYVDKDTLEANAHLVYAVHNDSHGLFRPDCHAYEADHTGRP 329
Fly 330 HTIVSCQLRFSRNGVFRETPYCVSLEARDLTIVSRVDAMSATANVCYHINLSKLHESEQELPQAL 394
Fly 395 PLRARQHRIFESEEFNGDSAGRSLSPPTVDYDKDVSVYRSAASNFRVVQPDSF-LDLMRLRSIRF 458
Fly 459 DIVEDKLGAFGITSTSGIVFVKN---PQVLEEAPETIYFLNVTWIDQQRLSHVRVINVHLVHGRP 520
Fly 521 ENTSCELKVKSRSQTCAQIKYQSQCVRYCGLATGGGSCQWRGSNSAMFGTRYGS-CVPESRYC-- 582
Fly 583 --PDHVCDPLEELNP-----MACPQD-----------------CTPAGRIVGPHSSNENKRGIYS 623
Fly 624 ASGT---CICEDNGKC---------------------------SCAPLDE--------EPKMKK- 649
Fly 650 ---PRKRKNETE----------------------------AEPLLGVRRGTPPNQPLQDPMLLG- 682
Fly 683 VLNVAGFECDRSC-----------------------------------MFFVIT----CPLLFVL 708
Fly 709 LLLCLLIAQRKMLQRRLGKQSMTTS----SKQALPESGGGDFALMPLQSGFRFESGDAKWEFPRE 769
Fly 770 KLQLDTVLGEGEFGQVLKGF---ATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEVSH 831
Fly 832 PNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVDFADGVEPVNVKMVLTFAWQIC 896
Fly 897 KGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPESLA 961
Fly 962 DHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWA 1026
Fly 1027 DEPNGRPSFKFLASEFEKLLGNNAKYIDLETNAVSN-PLYCG-DDSALI-----TTE----LGEP 1080
Fly 1081 ES-LQHLWSP-PKIAYDIHDQ----------------ATSYDQSEEEMPVTSTAPPGYDLPRPLL 1127
Fly 1128 DATANGQVLRYENDLRFPLNIRKSSCTPSYSNMTS-EPPATTSLPHYSVPVKRGRSYLDMTNKSL 1191
Fly 1192 IPDNLDSREF----------EKHL-SKTISFRFSSLLNLSETKEVSPG 1228 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Ret | NP_477044.1 | PKc_like | 770..1049 | CDD:304357 | 102/281 (36%) |
TyrKc | 771..1042 | CDD:197581 | 101/273 (37%) | ||
Egfr | NP_476759.1 | Recep_L_domain | 419..547 | CDD:279382 | 41/258 (16%) |
GF_recep_IV | 572..684 | CDD:291509 | 22/122 (18%) | ||
FU | 573..>606 | CDD:238021 | 4/32 (13%) | ||
FU | 617..659 | CDD:214589 | 11/42 (26%) | ||
FU | 662..716 | CDD:214589 | 9/54 (17%) | ||
FU | 739..786 | CDD:238021 | 10/46 (22%) | ||
FU | 784..834 | CDD:214589 | 9/54 (17%) | ||
PTKc_EGFR_like | 930..1208 | CDD:270648 | 104/309 (34%) | ||
STYKc | 938..1194 | CDD:214568 | 102/287 (36%) | ||
Recep_L_domain | 128..239 | CDD:279382 | 13/75 (17%) | ||
Furin-like | 253..401 | CDD:279142 | 31/180 (17%) | ||
FU | 255..292 | CDD:214589 | 8/49 (16%) | ||
FU | 302..345 | CDD:238021 | 10/60 (17%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C45455297 | |
Domainoid | 1 | 1.000 | 165 | 1.000 | Domainoid score | I1208 |
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | P | PTHR24416 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.940 |