DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ret and CG10702

DIOPT Version :9

Sequence 1:	NP_477044.1	Gene:	Ret / 43875	FlyBaseID:	FBgn0011829	Length:	1235	Species:	Drosophila melanogaster
Sequence 2:	NP_001188841.1	Gene:	CG10702 / 35181	FlyBaseID:	FBgn0032752	Length:	946	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	48/219 - (21%)
Similarity:	78/219 - (35%)	Gaps:	64/219 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   471 TSTSGIVFVKNPQVLEEAPETIYFLNVTWIDQQRLSHVRVINVHLVHGRPENTSCELKVKSRSQT 535
            |...|:|.:           |..|.::|.|..:||.....:.|..:|...:....:|....|.|.
  Fly    86 TDVRGLVNI-----------TEMFPHLTVIRGRRLFLNYALGVTNMHELEQLVFPKLVAIQRGQV 139

  Fly   536 CAQIKYQSQCVRYCGLATGGGSCQW------RGSNSAMF-----------GTRYGSCVPESRYCP 583
                 |...|.:.|.:    |...|      ||.|:.:.           |.....|. .:.||.
  Fly   140 -----YIGSCPKLCSI----GRVNWDLLTLTRGENNIIMVNKNCSTPVCSGCSSSHCW-SNHYCQ 194

  Fly   584 ----DHVCDPLEELNPMACPQDCTPAGRIVGPHSSNENKRGIYSASGTCIC---EDNGKC--SCA 639
                ::|.:|...:|  ||.::|      :|...:|.:     |.:...:|   .|:|.|  ||
  Fly   195 RSINENVANPKANIN--ACHEEC------LGGCKNNSS-----SPADCSVCRGLSDDGVCVKSC- 245

  Fly   640 PLDEEPKMKKPRKRKNETEAEPLL 663
            |.|   |......::..|:||.:|
  Fly   246 PKD---KYVMENYQRCYTKAECVL 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	PKc_like	770..1049	CDD:304357
Ret	NP_477044.1	TyrKc	771..1042	CDD:197581
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382	19/92 (21%)
		Furin-like	171..297	CDD:279142	26/114 (23%)
		FU	210..258	CDD:238021	15/62 (24%)
		Recep_L_domain	328..441	CDD:279382
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100