Protein Alignment Ret and Srms

DIOPT Version :10

• Sequence 1: NP_477044.1
• Gene: Ret / 43875
• FlyBaseID: FBgn0011829
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: NP_035611.4
• Gene: Srms / 20811
• MGIID: 101865
• Length: 496
• Species: Mus musculus
• Alignment Length: 346
• Identity: 119/346 - (34%)
• Similarity: 172/346 - (49%)
• Gaps: 65/346 - (18%)

  Fly   751 LQSGFRFESGDA-----------------------------KWEFPREKLQLDTVLGEGEFGQVL 786
            ||.|..|.|.||                             :||.||.:..|...||||.||:|.
Mouse   185 LQEGQLFPSLDALLAYYKTNWKLIQNPLLQPCIPQIPLVQDEWERPRSEFVLRRKLGEGFFGEVW 249

  Fly   787 KGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEVSHPNVIKLLGACTSSEAPLLII 851
            :|.  .:..:|    ||||::|  |..::...|..|.:.|:.:.|..:|:|...|:..|...::.
Mouse   250 EGL--WLGSIP----VAVKVIK--SADMKLADLTKEIEALKSLRHERLIRLHAICSLGEPVYIVT 306

  Fly   852 EYARYGSLRSYLRLSRKIECAGVDFADGVEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARN 916
            |....|:|:.||..|           :| :.:::..:|.||.|:.:||:||.|.::|||||||||
Mouse   307 ELMGKGNLQVYLGSS-----------EG-KALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARN 359

  Fly   917 VLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWEL 981
            ||:.|...||::||||.| :.:||.|...|..::||||.|||:....|::.||||||||:|.:|:
Mouse   360 VLVGDDLTCKVADFGLAR-LLKDDVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEV 423

  Fly   982 ITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKLL 1046
            .|.|..||.|:........:..|||:.||..|...||.::..||...|..||:|..|.   |||
Mouse   424 FTYGQCPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFAILR---EKL- 484

  Fly  1047 GNNAKYIDLETNAVSNPLYCG 1067
                       ||::..|:.|
Mouse   485 -----------NAINRRLHLG 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ret	NP_477044.1	Protein Kinases, catalytic domain	770..1049	CDD:473864	104/278 (37%)
Srms	NP_035611.4	None